Description
| Product Name: | OsIRE1 Rabbit pAb |
| Product Code: | CAB20585 |
| Size: | 50uL, 100uL |
| Synonyms: | OsIRE1 |
| Applications: | WB |
| Reactivity: | Oryza sativa |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of Oryza sativa OsIRE1 |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Oryza sativa |
| Positive Samples: | Leaves |
| Immunogen: | Recombinant protein of Oryza sativa OsIRE1 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 4343198 |
| Uniprot: | Q7XIT1 |
| Calculated MW: | 99kDa |
| Observed MW: | 90kDa |
| Background: | Involved in endoplasmic reticulum (ER) stress response. Senses unfolded proteins in the lumen of the ER via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices bZIP50 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response (UPR) transcriptional activator, which then induces transcription of UPR target genes, such as luminal-binding protein (BiP) chaperones. |