Description
Product Name: | OsIRE1 Rabbit pAb |
Product Code: | CAB20585 |
Size: | 50uL, 100uL |
Synonyms: | OsIRE1 |
Applications: | WB |
Reactivity: | Oryza sativa |
Host Species: | Rabbit |
Immunogen: | Recombinant protein of Oryza sativa OsIRE1 |
Applications: | WB |
Recommended Dilutions: | WB 1:500 - 1:2000 |
Reactivity: | Oryza sativa |
Positive Samples: | Leaves |
Immunogen: | Recombinant protein of Oryza sativa OsIRE1 |
Purification Method: | Affinity purification |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 4343198 |
Uniprot: | Q7XIT1 |
Calculated MW: | 99kDa |
Observed MW: | 90kDa |
Background: | Involved in endoplasmic reticulum (ER) stress response. Senses unfolded proteins in the lumen of the ER via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices bZIP50 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response (UPR) transcriptional activator, which then induces transcription of UPR target genes, such as luminal-binding protein (BiP) chaperones. |