Epigenetics & Nuclear Signaling Antibodies 4

Anti-OSGEP Antibody (CAB7473)

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SKU:
CAB7473
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-OSGEP Antibody
Antibody SKU:CAB7473
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-335 of human OSGEP (NP_060277.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:HL-60, Raji, Jurkat, 293T, Mouse heart, Mouse skeletal muscle, Mouse ovary, Rat heart, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-335 of human OSGEP (NP_060277.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MPAV LGFE GSAN KIGV GVVR DGKV LANP RRTY VTPP GTGF LPGD TARH HRAV ILDL LQEA LTES GLTS QDID CIAY TKGP GMGA PLVS VAVV ARTV AQLW NKPL VGVN HCIG HIEM GRLI TGAT SPTV LYVS GGNT QVIA YSEH RYRI FGET IDIA VGNC LDRF ARVL KISN DPSP GYNI EQMA KRGK KLVE LPYT VKGM DVSF SGIL SFIE DVAH RMLA TGEC TPED LCFS LQET VFAM LVEI TERA MAHC GSQE ALIV GGVG CNVR LQEM MATM CQER GARL FATD ERFC IDNG AMIA QAGW EMFR AGHR TPLS DSGV TQRY RTDE VEVT WRD
Gene ID:55644
Uniprot:Q9NPF4
Cellular Location:Cytoplasm, Nucleus
Calculated MW:36kDa
Observed MW:36kDa
Synonyms:OSGEP, GCPL1, KAE1, OSGEP1, PRSMG1, TCS3
Background:
UniProt Protein Function:OSGEP: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Belongs to the KAE1 / YgjD family.
UniProt Protein Details:

Protein type:Protease; EC 2.6.99.4

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: cytoplasm; nucleus

Molecular Function:metal ion binding; transferase activity, transferring groups other than amino-acyl groups

UniProt Code:Q9NPF4
NCBI GenInfo Identifier:47605574
NCBI Gene ID:55644
NCBI Accession:Q9NPF4.1
UniProt Secondary Accession:Q9NPF4,Q6IAC3,
UniProt Related Accession:Q9NPF4
Molecular Weight:335
NCBI Full Name:Probable tRNA N6-adenosine threonylcarbamoyltransferase
NCBI Synonym Full Names:O-sialoglycoprotein endopeptidase
NCBI Official Symbol:OSGEP  
NCBI Official Synonym Symbols:KAE1; GCPL1; OSGEP1; PRSMG1  
NCBI Protein Information:probable tRNA N6-adenosine threonylcarbamoyltransferase; OSGEP; hOSGEP; t(6)A synthase; N6-L-threonylcarbamoyladenine synthase; probable O-sialoglycoprotein endopeptidase; tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP; t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP; probable tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP
UniProt Protein Name:Probable tRNA N6-adenosine threonylcarbamoyltransferase
UniProt Synonym Protein Names:N6-L-threonylcarbamoyladenine synthase; t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP; tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP
Protein Family:Probable tRNA N6-adenosine threonylcarbamoyltransferase
UniProt Gene Name:OSGEP  
UniProt Entry Name:OSGEP_HUMAN
Anti-OSGEP Antibody (CAB7473)Western blot analysis of extracts of various cell lines, using OSGEP antibody (CAB7473) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
Anti-OSGEP Antibody (CAB7473)Immunofluorescence analysis of A549 cells using OSGEP antibody (CAB7473). Blue: DAPI for nuclear staining.
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