Cell Biology Antibodies 15

Anti-OSBPL8 Antibody (CAB17816)

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SKU:
CAB17816
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-OSBPL8 Antibody
Antibody SKU:CAB17816
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human OSBPL8 (NP_065892.1).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse spleen, Mouse kidney, Rat thymus, Rat kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human OSBPL8 (NP_065892.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MEGG LADG EPDR TSLL GDSK DVLG PSTV VANS DESQ LLTP GKMS QRQG KEAY PTPT KDLH QPSL SPAS PHSQ GFER GKED ISQN KDES SLSM SKSK SESK LYNG SEKD SS
Gene ID:114882
Uniprot:Q9BZF1
Cellular Location:
Calculated MW:
Observed MW:101kDa
Anti-OSBPL8 Antibody (CAB17816)Western blot - OSBPL8 Rabbit pAb (CAB17816)
Synonyms:MST120, MSTP120, ORP8, OSBP10, OSBPL8
Background:This gene encodes a member of a family of proteins containing an N-terminal pleckstrin homology domain and a highly conserved C-terminal oxysterol-binding protein-like sterol-binding domain. It binds mutliple lipid-containing molecules, including phosphatidylserine, phosphatidylinositol 4-phosphate (PI4P) and oxysterol, and promotes their exchange between the endoplasmic reticulum and the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
UniProt Protein Function:OSBPL8: a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Two splice variant isoforms have been described.
UniProt Protein Details:

Protein type:Unknown function

Chromosomal Location of Human Ortholog: 12q14

Cellular Component: membrane

Molecular Function:cholesterol binding; phosphatidylserine binding; phospholipid transporter activity

Biological Process: activation of protein kinase B; fat cell differentiation; phospholipid transport; positive regulation of protein kinase B signaling cascade

NCBI Summary:This gene encodes a member of a family of proteins containing an N-terminal pleckstrin homology domain and a highly conserved C-terminal oxysterol-binding protein-like sterol-binding domain. It binds mutliple lipid-containing molecules, including phosphatidylserine, phosphatidylinositol 4-phosphate (PI4P) and oxysterol, and promotes their exchange between the endoplasmic reticulum and the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
UniProt Code:Q9BZF1
NCBI GenInfo Identifier:84627542
NCBI Gene ID:114882
NCBI Accession:BC111728
UniProt Secondary Accession:Q9BZF1,Q52LQ3, Q68D75, Q8WXP8, Q9P277, A8K1T2, E9PE66 E9PE68,
UniProt Related Accession:Q9BZF1
Molecular Weight:96,956 Da
NCBI Full Name:Homo sapiens oxysterol binding protein-like 8, transcript variant 1, mRNA
NCBI Synonym Full Names:oxysterol binding protein like 8
NCBI Official Symbol:OSBPL8  
NCBI Official Synonym Symbols:ORP8; MST120; OSBP10; MSTP120  
NCBI Protein Information:oxysterol-binding protein-related protein 8
UniProt Protein Name:Oxysterol-binding protein-related protein 8
Protein Family:Oxysterol-binding protein-related protein
UniProt Gene Name:OSBPL8  
UniProt Entry Name:OSBL8_HUMAN
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