Cell Biology Antibodies 4

Anti-OSBPL2 Antibody (CAB14199)

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SKU:
CAB14199
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-OSBPL2 Antibody
Antibody SKU:CAB14199
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 291-480 of human OSBPL2 (NP_653081.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:U-251MG, A-549, HepG2, HeLa
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 291-480 of human OSBPL2 (NP_653081.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:NKKK LFMI YGKW TECL WGID PVSY ESFK KQER RGDH LRKA KLDE DSGK ADSD VADD VPVA QETV QVIP GSKL LWRI NTRP PNSA QMYN FTSF TVSL NELE TGME KTLP PTDC RLRP DIRG MENG NMDL ASQE KERL EEKQ REAR RERA KEEA EWQT RWFY PGNN PYTG TPDW LYAG DYFE RNFS DCPD IY
Gene ID:9885
Uniprot:Q9H1P3
Cellular Location:
Calculated MW:53kDa/55kDa
Observed MW:56kDa
Synonyms:OSBPL2, DFNA67, DNFA67, ORP-2, ORP2
Background:This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.
UniProt Code:Q9H1P3
NCBI GenInfo Identifier:7662298
NCBI Gene ID:9885
NCBI Accession:NP_055650
UniProt Secondary Accession:Q9H1P3,Q8BX94,
UniProt Related Accession:Q6ZTC4,Q9H1P3
Molecular Weight:53,971 Da
NCBI Full Name:oxysterol-binding protein-related protein 2 isoform 1
NCBI Synonym Full Names:oxysterol binding protein-like 2
NCBI Official Symbol:OSBPL2  
NCBI Official Synonym Symbols:ORP2; ORP-2; DFNA67  
NCBI Protein Information:oxysterol-binding protein-related protein 2; OSBP-related protein 2; oxysterol-binding protein-like 2
UniProt Protein Name:Oxysterol-binding protein-related protein 2
UniProt Gene Name:OSBPL2  
UniProt Entry Name:OSBL2_HUMAN
Anti-OSBPL2 Antibody (CAB14199)Western blot analysis of extracts of various cell lines, using OSBPL2 antibody (CAB14199) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
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