Cell Biology Antibodies 12
Anti-OPRD1 Antibody (CAB8445)
- SKU:
- CAB8445
Description
| Antibody Name: | Anti-OPRD1 Antibody |
| Antibody SKU: | CAB8445 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human OPRD1 (NP_000902.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse brain, Rat brain |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human OPRD1 (NP_000902.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LHLC IALG YANS SLNP VLYA FLDE NFKR CFRQ LCRK PCGR PDPS SFSR AREA TARE RVTA CTPS DGPG GGAA A |
| Gene ID: | 4985 |
| Uniprot: | P41143 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 40kDa |
| Observed MW: | 43kDa |
| Synonyms: | OPRD1, OPRD |
| Background: |
| UniProt Protein Function: | DOR-1: delta opioid receptor, a G-protein coupled receptor. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. Receptor for enkephalins. |
| UniProt Protein Details: | Protein type:GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral Chromosomal Location of Human Ortholog: 1p36.1-p34.3 Cellular Component: cytoplasm; integral to plasma membrane; intrinsic to plasma membrane; lipid raft; nerve terminal; neuron projection; plasma membrane; postsynaptic membrane; vesicle Molecular Function:neuropeptide binding; opioid receptor activity; protein binding Biological Process: activation of CREB transcription factor; adult locomotory behavior; eating behavior; G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase inhibiting pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); immune response; negative regulation of protein oligomerization; neuropeptide signaling pathway; positive regulation of peptidyl-serine phosphorylation; protein import into nucleus, translocation; regulation of calcium ion transport; regulation of mitochondrial membrane potential; regulation of sensory perception of pain; synaptic transmission |
| UniProt Code: | P41143 |
| NCBI GenInfo Identifier: | 311033488 |
| NCBI Gene ID: | 4985 |
| NCBI Accession: | P41143.4 |
| UniProt Secondary Accession: | P41143,B5B0B8, |
| UniProt Related Accession: | P41143 |
| Molecular Weight: | 40,369 Da |
| NCBI Full Name: | Delta-type opioid receptor |
| NCBI Synonym Full Names: | opioid receptor delta 1 |
| NCBI Official Symbol: | OPRD1 |
| NCBI Official Synonym Symbols: | OPRD |
| NCBI Protein Information: | delta-type opioid receptor |
| UniProt Protein Name: | Delta-type opioid receptor |
| Protein Family: | Delta-type opioid receptor |
| UniProt Gene Name: | OPRD1 |
| UniProt Entry Name: | OPRD_HUMAN |
 | Western blot analysis of extracts of various cell lines, using OPRD1 antibody (CAB8445) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
Additional Information
Product Type: |
Antibody |
Applications: |
WB |
Reactivity: |
Mouse |
Reactivity: |
Rat |
Host Species: |
Rabbit |
Isotype: |
IgG |
Research Area: |
Cell Biology |
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