Neuroscience

Anti-OPN5 Antibody (CAB15971)

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SKU:
CAB15971
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Neuroscience

Description

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Antibody Name:Anti-OPN5 Antibody
Antibody SKU:CAB15971
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 200-300 of human OPN5 (NP_859528.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:U-251MG, HeLa, Mouse eye, Mouse brain, Mouse testis, Rat eye, Rat brain
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 200-300 of human OPN5 (NP_859528.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:ILNI LFFC LLLP TAVI VFSY VKII AKVK SSSK EVAH FDSR IHSS HVLE MKLT KVAM LICA GFLI AWIP YAVV SVWS AFGR PDSI PIQL SVVP TLLA KSAA M
Gene ID:221391
Uniprot:Q6U736
Cellular Location:Membrane, Multi-pass membrane protein
Calculated MW:39kDa
Observed MW:42kDa
Synonyms:OPN5, GPR136, GRP136, PGR12, TMEM13, opsin-5
Background:Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This opsin gene is expressed in the eye, brain, testes, and spinal cord. This gene belongs to the seven-exon subfamily of mammalian opsin genes that includes peropsin (RRH) and retinal G protein coupled receptor (RGR). Like these other seven-exon opsin genes, this family member may encode a protein with photoisomerase activity. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:neuropsin: Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This opsin gene is expressed in the eye, brain, testes, and spinal cord. This gene belongs to the seven-exon subfamily of mammalian opsin genes that includes peropsin (RRH) and retinal G protein coupled receptor (RGR). Like these other seven-exon opsin genes, this family member may encode a protein with photoisomerase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
UniProt Protein Details:

Protein type:GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 6p12.3

Cellular Component: integral to membrane

Molecular Function:11-cis retinal binding; G-protein coupled receptor activity; photoreceptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; phototransduction; protein-chromophore linkage; visual perception

NCBI Summary:Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This opsin gene is expressed in the eye, brain, testes, and spinal cord. This gene belongs to the seven-exon subfamily of mammalian opsin genes that includes peropsin (RRH) and retinal G protein coupled receptor (RGR). Like these other seven-exon opsin genes, this family member may encode a protein with photoisomerase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
UniProt Code:Q6U736
NCBI GenInfo Identifier:38678524
NCBI Gene ID:221391
NCBI Accession:NP_859528.1
UniProt Secondary Accession:Q6U736,Q5T5B9, Q5T886, Q7Z603, Q86SL5, A0AV33,
UniProt Related Accession:Q6U736
Molecular Weight:39,727 Da
NCBI Full Name:opsin-5
NCBI Synonym Full Names:opsin 5
NCBI Official Symbol:OPN5  
NCBI Official Synonym Symbols:PGR12; GPR136; GRP136; TMEM13  
NCBI Protein Information:opsin-5
UniProt Protein Name:Opsin-5
UniProt Synonym Protein Names:G-protein coupled receptor 136; G-protein coupled receptor PGR12; Neuropsin; Transmembrane protein 13
Protein Family:Opsin
UniProt Gene Name:OPN5  
UniProt Entry Name:OPN5_HUMAN
Anti-OPN5 Antibody (CAB15971)Western blot analysis of extracts of various cell lines, using OPN5 antibody (CAB15971) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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