Name: Anti-OPN5 Antibody (CAB15971)
Brand: Neuroscience
SKU: CAB15971
Availability: OutOfStock

Antibody Name:	Anti-OPN5 Antibody
Antibody SKU:	CAB15971
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 200-300 of human OPN5 (NP_859528.1).

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Human, Mouse, Rat
Positive Samples:	U-251MG, HeLa, Mouse eye, Mouse brain, Mouse testis, Rat eye, Rat brain

Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 200-300 of human OPN5 (NP_859528.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	ILNI LFFC LLLP TAVI VFSY VKII AKVK SSSK EVAH FDSR IHSS HVLE MKLT KVAM LICA GFLI AWIP YAVV SVWS AFGR PDSI PIQL SVVP TLLA KSAA M
Gene ID:	221391
Uniprot:	Q6U736
Cellular Location:	Membrane, Multi-pass membrane protein
Calculated MW:	39kDa
Observed MW:	42kDa

Synonyms:

OPN5, GPR136, GRP136, PGR12, TMEM13, opsin-5

Background:

Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This opsin gene is expressed in the eye, brain, testes, and spinal cord. This gene belongs to the seven-exon subfamily of mammalian opsin genes that includes peropsin (RRH) and retinal G protein coupled receptor (RGR). Like these other seven-exon opsin genes, this family member may encode a protein with photoisomerase activity. Alternative splicing results in multiple transcript variants.

UniProt Protein Function:	neuropsin: Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This opsin gene is expressed in the eye, brain, testes, and spinal cord. This gene belongs to the seven-exon subfamily of mammalian opsin genes that includes peropsin (RRH) and retinal G protein coupled receptor (RGR). Like these other seven-exon opsin genes, this family member may encode a protein with photoisomerase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
UniProt Protein Details:	Protein type:GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 6p12.3 Cellular Component: integral to membrane Molecular Function:11-cis retinal binding; G-protein coupled receptor activity; photoreceptor activity Biological Process: G-protein coupled receptor protein signaling pathway; phototransduction; protein-chromophore linkage; visual perception
NCBI Summary:	Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This opsin gene is expressed in the eye, brain, testes, and spinal cord. This gene belongs to the seven-exon subfamily of mammalian opsin genes that includes peropsin (RRH) and retinal G protein coupled receptor (RGR). Like these other seven-exon opsin genes, this family member may encode a protein with photoisomerase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
UniProt Code:	Q6U736
NCBI GenInfo Identifier:	38678524
NCBI Gene ID:	221391
NCBI Accession:	NP_859528.1
UniProt Secondary Accession:	Q6U736,Q5T5B9, Q5T886, Q7Z603, Q86SL5, A0AV33,
UniProt Related Accession:	Q6U736
Molecular Weight:	39,727 Da
NCBI Full Name:	opsin-5
NCBI Synonym Full Names:	opsin 5
NCBI Official Symbol:	OPN5
NCBI Official Synonym Symbols:	PGR12; GPR136; GRP136; TMEM13
NCBI Protein Information:	opsin-5
UniProt Protein Name:	Opsin-5
UniProt Synonym Protein Names:	G-protein coupled receptor 136; G-protein coupled receptor PGR12; Neuropsin; Transmembrane protein 13
Protein Family:	Opsin
UniProt Gene Name:	OPN5
UniProt Entry Name:	OPN5_HUMAN

Western blot analysis of extracts of various cell lines, using OPN5 antibody (CAB15971) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.

Antibodies

OPN5 Antibody (PACO02707)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)