Cell Biology Antibodies 14
Anti-OLFM4 Antibody (CAB17081)
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- SKU:
- CAB17081
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-OLFM4 Antibody |
| Antibody SKU: | CAB17081 |
| Antibody Size: | 20uL, 50 uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 211-510 of human OLFM4 (NP_006409.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 211-510 of human OLFM4 (NP_006409.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | AIRR EIVA LKTK LKEC EASK DQNT PVVH PPPT PGSC GHGG VVNI SKPS VVQL NWRG FSYL YGAW GRDY SPQH PNKG LYWV APLN TDGR LLEY YRLY NTLD DLLL YINA RELR ITYG QGSG TAVY NNNM YVNM YNTG NIAR VNLT TNTI AVTQ TLPN AAYN NRFS YANV AWQD IDFA VDEN GLWV IYST EAST GNMV ISKL NDTT LQVL NTWY TKQY KPSA SNAF MVCG VLYA TRTM NTRT EEIF YYYD TNTG KEGK LDIV MHKM QEKV QSIN YNPF DQKL YVYN DGYL LNYD LSVL QKPQ |
| Gene ID: | 10562 |
| Uniprot: | Q6UX06 |
| Cellular Location: | |
| Calculated MW: | 57kDa |
| Observed MW: | Refer to figures |
| Synonyms: | OLFM4, GC1, GW112, OLM4, OlfD, UNQ362, bA209J19.1, hGC-1, hOLfD |
| Background: | This gene was originally cloned from human myeloblasts and found to be selectively expressed in inflammed colonic epithelium. This gene encodes a member of the olfactomedin family. The encoded protein is an antiapoptotic factor that promotes tumor growth and is an extracellular matrix glycoprotein that facilitates cell adhesion. |
| UniProt Protein Function: | May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin. |
| NCBI Summary: | This gene was originally cloned from human myeloblasts and found to be selectively expressed in inflammed colonic epithelium. This gene encodes a member of the olfactomedin family. The encoded protein is an antiapoptotic factor that promotes tumor growth and is an extracellular matrix glycoprotein that facilitates cell adhesion. [provided by RefSeq, Mar 2011] |
| UniProt Code: | Q6UX06 |
| NCBI GenInfo Identifier: | 32313593 |
| NCBI Gene ID: | 10562 |
| NCBI Accession: | NP_006409.3 |
| UniProt Secondary Accession: | Q6UX06,O95362, Q5VWG0, Q86T22, |
| UniProt Related Accession: | Q6UX06 |
| Molecular Weight: | 57,280 Da |
| NCBI Full Name: | olfactomedin-4 |
| NCBI Synonym Full Names: | olfactomedin 4 |
| NCBI Official Symbol: | OLFM4 |
| NCBI Official Synonym Symbols: | GC1; OLM4; OlfD; GW112; hGC-1; hOLfD; UNQ362; bA209J19.1 |
| NCBI Protein Information: | olfactomedin-4 |
| UniProt Protein Name: | Olfactomedin-4 |
| UniProt Synonym Protein Names: | Antiapoptotic protein GW112; G-CSF-stimulated clone 1 protein; hGC-1; hOLfD |
| Protein Family: | Olfactomedin |
| UniProt Gene Name: | OLFM4 |
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