Anti-ODC1 Antibody (CAB3898)
- SKU:
- CAB3898
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ODC
- Research Area:
- Metabolism
Description
| Product Name: | ODC1 Rabbit mAb |
| Product Code: | CAB3898 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | ODC |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human ODC1 |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | U-937 |
| Immunogen: | A synthesized peptide derived from human ODC1 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 4953 |
| Uniprot: | P11926 |
| Calculated MW: | 51kDa |
| Observed MW: | 53KDa |
| UniProt Protein Function: | ODC: the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Other Amino Acids Metabolism - glutathione; EC 4.1.1.17; Cell cycle regulation; Lyase; Amino Acid Metabolism - arginine and proline Chromosomal Location of Human Ortholog: 2p25 Cellular Component: cytoplasm; cytosol Molecular Function:ornithine decarboxylase activity; protein binding; protein homodimerization activity Biological Process: polyamine metabolic process; putrescine biosynthetic process from ornithine; regulation of amino acid metabolic process; regulation of protein catabolic process; response to virus Disease: Colorectal Cancer |
| NCBI Summary: | This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2013] |
| UniProt Code: | P11926 |
| NCBI GenInfo Identifier: | 118377 |
| NCBI Gene ID: | 4953 |
| NCBI Accession: | P11926.2 |
| UniProt Secondary Accession: | P11926,Q53TU3, Q6LDS9, |
| UniProt Related Accession: | P11926 |
| Molecular Weight: | 51,148 Da |
| NCBI Full Name: | Ornithine decarboxylase |
| NCBI Synonym Full Names: | ornithine decarboxylase 1 |
| NCBI Official Symbol: | ODC1 |
| NCBI Official Synonym Symbols: | ODC |
| NCBI Protein Information: | ornithine decarboxylase |
| UniProt Protein Name: | Ornithine decarboxylase |
| Protein Family: | Mitochondrial 2-oxodicarboxylate carrier |
| UniProt Gene Name: | ODC1 |
| UniProt Entry Name: | DCOR_HUMAN |
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