Epigenetics & Nuclear Signaling Antibodies 1

Anti-NXT2 Antibody (CAB13822)

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SKU:
CAB13822
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-NXT2 Antibody
Antibody SKU:CAB13822
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 110-180 of human NXT2 (NP_061168.2).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse testis, Rat testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 110-180 of human NXT2 (NP_061168.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:GLDA LNNF FDTL PSSE FQVN MLDC QPVH EQAT QSQT TVLV VTSG TVKF DGNK QHFF NQNF LLTA QSTP NNT
Gene ID:55916
Uniprot:Q9NPJ8
Cellular Location:Cytoplasm, Nucleus
Calculated MW:12kDa/16kDa/21kDa/22kDa
Observed MW:16kDa
Synonyms:NXT2, P15-2
Background:The protein encoded by this gene contains a nuclear transport factor 2 (NTF2) domain, which plays an important role in the trafficking of macromolecules, ions, and small molecules between the cytoplasm and nucleus. This protein may also have a role in mRNA nuclear export. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
UniProt Protein Function:Regulator of protein export for NES-containing proteins. Also plays a role in mRNA nuclear export.
NCBI Summary:The protein encoded by this gene contains a nuclear transport factor 2 (NTF2) domain, which plays an important role in the trafficking of macromolecules, ions, and small molecules between the cytoplasm and nucleus. This protein may also have a role in mRNA nuclear export. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jun 2011]
UniProt Code:Q9NPJ8
NCBI GenInfo Identifier:336176110
NCBI Gene ID:55916
NCBI Accession:NP_001229546.1
UniProt Secondary Accession:Q9NPJ8,Q0VAN8, Q5JYV5, Q5JYV6, Q5JYV7, Q9H8U0, Q9NQ64 Q9NRL7, Q9Y3M4, Q9Y3M5, D3DUY1,
UniProt Related Accession:Q9NPJ8
Molecular Weight:Calculated: 12kDa; 16kDa; 21kDa; 22kDaObserved: 16kDa
NCBI Full Name:NTF2-related export protein 2 isoform 2
NCBI Synonym Full Names:nuclear transport factor 2 like export factor 2
NCBI Official Symbol:NXT2  
NCBI Official Synonym Symbols:P15-2  
NCBI Protein Information:NTF2-related export protein 2
UniProt Protein Name:NTF2-related export protein 2
UniProt Synonym Protein Names:Protein p15-2
Protein Family:NTF2-related export protein
UniProt Gene Name:NXT2  
Anti-NXT2 Antibody (CAB13822)Western blot analysis of extracts of various cell lines, using NXT2 antibody (CAB13822) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
Anti-NXT2 Antibody (CAB13822)Immunofluorescence analysis of L929 cells using NXT2 antibody (CAB13822) at dilution of 1:100. Blue: DAPI for nuclear staining.
Anti-NXT2 Antibody (CAB13822)Immunofluorescence analysis of U-2 OS cells using NXT2 antibody (CAB13822) at dilution of 1:100. Blue: DAPI for nuclear staining.
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