Epigenetics & Nuclear Signaling Antibodies 1
Anti-NUPL2 Antibody (CAB10779)
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- SKU:
- CAB10779
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-NUPL2 Antibody |
| Antibody SKU: | CAB10779 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human NUPL2 (NP_031368.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | HeLa, A-549, A-431, SGC-7901 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human NUPL2 (NP_031368.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAIC QFFL QGRC RFGD RCWN EHPG ARGA GGGR QQPQ QQPS GNNR RGWN TTSQ RYSN VIQP SSFS KSTP WGGS RDQE KPYF SSFD SGAS TNRK EGFG LSEN PFAS LSPD EQKD EKKL LEGI VKDM EVWE SSGQ WMFS VYSP VKKK PNIS GFTD ISPE ELRL EYHN FLTS NNLQ SYLN SVQR LINQ WRNR VNEL KSLN ISTK |
| Gene ID: | 11097 |
| Uniprot: | O15504 |
| Cellular Location: | Cytoplasmic side, Nucleus, Nucleus membrane, Peripheral membrane protein, nuclear pore complex |
| Calculated MW: | 19kDa/25kDa/44kDa |
| Observed MW: | 45kDa |
| Synonyms: | NUPL2, CG1, NLP-1, NLP_1, hCG1 |
| Background: |
| UniProt Protein Function: | NUPL2: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Nucleoporin Chromosomal Location of Human Ortholog: 7p15.3 Cellular Component: cytosol; nuclear envelope; nucleoplasm; nucleus Molecular Function:nuclear export signal receptor activity; protein binding; RNA binding Biological Process: mitotic nuclear envelope disassembly; mRNA export from nucleus; protein export from nucleus; protein sumoylation; RNA-mediated gene silencing; tRNA export from nucleus; viral reproduction; viral transcription |
| UniProt Code: | O15504 |
| NCBI GenInfo Identifier: | 74705530 |
| NCBI Gene ID: | 11097 |
| NCBI Accession: | O15504.1 |
| UniProt Secondary Accession: | O15504,Q49AE7, Q9BS49, A4D143, B4DP42, |
| UniProt Related Accession: | O15504 |
| Molecular Weight: | 45kDa |
| NCBI Full Name: | Nucleoporin-like protein 2 |
| NCBI Synonym Full Names: | nucleoporin like 2 |
| NCBI Official Symbol: | NUPL2 |
| NCBI Official Synonym Symbols: | CG1; hCG1; NLP-1; NLP_1 |
| NCBI Protein Information: | nucleoporin-like protein 2 |
| UniProt Protein Name: | Nucleoporin-like protein 2 |
| UniProt Synonym Protein Names: | NLP-1; NUP42 homolog; Nucleoporin hCG1 |
| Protein Family: | Nucleoporin-like protein |
| UniProt Gene Name: | NUPL2 |
 | Western blot analysis of extracts of various cell lines, using NUPL2 antibody (CAB10779) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
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