Cell Biology Antibodies 13

Anti-NUP58 Antibody (CAB17598)

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SKU:
CAB17598
Product Type:
Antibody
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-NUP58 Antibody
Antibody SKU:CAB17598
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Rat
Host Species:Rabbit
Immunogen:A synthetic peptide of Human NUP58.
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Rat
Positive Samples:Rat liver
Immunogen:A synthetic peptide of Human NUP58.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:9818
Uniprot:Q9BVL2
Cellular Location:
Calculated MW:
Observed MW:58kDa
Anti-NUP58 Antibody (CAB17598)Western blot - NUP58 Polyclonal Antibody (CAB17598)
Synonyms:NUP45, NUPL1, PRO2463, NUP58
Background:This gene encodes a member of the nucleoporin family that shares 87% sequence identity with rat nucleoporin p58. The protein is localized to the nuclear rim and is a component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
UniProt Protein Function:NUPL1: a nuclear pore protein. Component of the p62 complex which includes NUP62, NUP54, and NUPL1. Interacts with NUTF2, and with KPNA2 and KPNB1 proteins when they are together, but not with KPNA2 alone. Located in the central region of the nuclear pore complex, biased towards thecytoplasmic side. Contains FG repeats. Three isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Nucleoporin; Nuclear import

Chromosomal Location of Human Ortholog: 13q12.13

Cellular Component: nuclear envelope; nuclear pore

Molecular Function:nuclear localization sequence binding; nucleocytoplasmic transporter activity; protein binding

Biological Process: mitotic nuclear envelope disassembly; mRNA export from nucleus; protein import into nucleus; protein sumoylation; RNA-mediated gene silencing; tRNA export from nucleus; viral reproduction; viral transcription

NCBI Summary:This gene encodes a member of the nucleoporin family that shares 87% sequence identity with rat nucleoporin p58. The protein is localized to the nuclear rim and is a component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
UniProt Code:Q9BVL2
NCBI GenInfo Identifier:44888845
NCBI Gene ID:9818
NCBI Accession:Q9BVL2.1
UniProt Secondary Accession:Q9BVL2,O43160, Q5JRG2, Q5JRG5, A6NI12, B4DZJ1,
UniProt Related Accession:Q9BVL2
Molecular Weight:59,754 Da
NCBI Full Name:Nucleoporin p58/p45
NCBI Synonym Full Names:nucleoporin 58
NCBI Official Symbol:NUP58  
NCBI Official Synonym Symbols:NUP45; NUPL1; PRO2463  
NCBI Protein Information:nucleoporin p58/p45
UniProt Protein Name:Nucleoporin p58/p45
UniProt Synonym Protein Names:58 kDa nucleoporin
UniProt Gene Name:NUP58  
UniProt Entry Name:NUP58_HUMAN
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