Anti-NUP210 Antibody (CAB19895)

Name: Anti-NUP210 Antibody (CAB19895)[KO Validated]
Brand: KO Validated Antibodies 2
SKU: CAB19895
Availability: OutOfStock

Antibody Name:	Anti-NUP210 Antibody [KO Validated]
Antibody SKU:	CAB19895
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IF
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant protein of human NUP210.

Application:	WB IF
Recommended Dilution:	WB 1:1000 - 1:2000 IF 1:50 - 1:200
Reactivity:	Human, Mouse, Rat
Positive Samples:	293T

Immunogen:	Recombinant protein of human NUP210.
Purification Method:	Affinity purification
Storage Buffer:	Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	Email for sequence
Gene ID:	23225
Uniprot:	Q8TEM1
Cellular Location:
Calculated MW:	205kDa
Observed MW:	290KDa

Anti-NUP210 Antibody [KO Validated] (CAB19895)

Western blot analysis of extracts from normal (control) and NUP210 knockout (KO) 293T cells, using NUP210 antibody (CAB19895) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.

Synonyms:

NUP210, GP210, POM210

Background:

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a membrane-spanning glycoprotein that is a major component of the nuclear pore complex. Multiple pseudogenes related to this gene are located on chromosome 3.

UniProt Protein Function:	NUP210: Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity. Belongs to the NUP210 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:Nucleoporin; Membrane protein, integral Chromosomal Location of Human Ortholog: 3p25.1 Cellular Component: membrane; nuclear envelope; nuclear pore Biological Process: mitotic nuclear envelope disassembly; mRNA export from nucleus; protein sumoylation; RNA-mediated gene silencing; tRNA export from nucleus; viral reproduction; viral transcription
NCBI Summary:	The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a membrane-spanning glycoprotein that is a major component of the nuclear pore complex. Multiple pseudogenes related to this gene are located on chromosome 3. [provided by RefSeq, Jul 2013]
UniProt Code:	Q8TEM1
NCBI GenInfo Identifier:	116242720
NCBI Gene ID:	23225
NCBI Accession:	Q8TEM1.3
UniProt Secondary Accession:	Q8TEM1,O94980, Q6NXG6, Q8NBJ1, Q9H6C8, Q9UFP3, A6NN56
UniProt Related Accession:	Q8TEM1
Molecular Weight:	105,810 Da
NCBI Full Name:	Nuclear pore membrane glycoprotein 210
NCBI Synonym Full Names:	nucleoporin 210
NCBI Official Symbol:	NUP210
NCBI Official Synonym Symbols:	GP210; POM210
NCBI Protein Information:	nuclear pore membrane glycoprotein 210
UniProt Protein Name:	Nuclear pore membrane glycoprotein 210
UniProt Synonym Protein Names:	Nuclear envelope pore membrane protein POM 210; POM210; Nucleoporin Nup210; Pore membrane protein of 210 kDa
Protein Family:	Nuclear pore membrane glycoprotein
UniProt Gene Name:	NUP210
UniProt Entry Name:	PO210_HUMAN