Epigenetics & Nuclear Signaling Antibodies 1

Anti-NUP160 Antibody (CAB13080)

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SKU:
CAB13080
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-NUP160 Antibody
Antibody SKU:CAB13080
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 40-150 of human NUP160 (NP_056046.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:A-431, Jurkat, HepG2
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 40-150 of human NUP160 (NP_056046.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:ALER SFVE LSGA ERER PRHF REFT VCSI GTAN AVAG AVKY SESA GGFY YVES GKLF SVTR NRFI HWKT SGDT LELM EESL DINL LNNA IRLK FQNC SVLP GGVY VSET QNR
Gene ID:23279
Uniprot:Q12769
Cellular Location:Nucleus, nuclear pore complex
Calculated MW:24kDa/55kDa/162kDa
Observed MW:150kDa
Synonyms:NUP160
Background:
UniProt Protein Function:NUP160: Involved in poly(A)+ RNA transport. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Nucleoporin

Chromosomal Location of Human Ortholog: 11p11.2

Cellular Component: cytosol; kinetochore; nuclear envelope; nuclear pore

Molecular Function:nucleocytoplasmic transporter activity; protein binding

Biological Process: mitotic nuclear envelope disassembly; mRNA export from nucleus; protein sumoylation; RNA-mediated gene silencing; sister chromatid cohesion; tRNA export from nucleus; viral reproduction; viral transcription

NCBI Summary:NUP160 is 1 of up to 60 proteins that make up the 120-MD nuclear pore complex, which mediates nucleoplasmic transport.[supplied by OMIM, Apr 2004]
UniProt Code:Q12769
NCBI GenInfo Identifier:238054372
NCBI Gene ID:23279
NCBI Accession:Q12769.3
UniProt Secondary Accession:Q12769,Q08AD3, Q7Z5X6, Q96GB3, Q9H660, B4DYE8, B4E2J9
UniProt Related Accession:Q12769
Molecular Weight:55,554 Da
NCBI Full Name:Nuclear pore complex protein Nup160
NCBI Synonym Full Names:nucleoporin 160
NCBI Official Symbol:NUP160  
NCBI Protein Information:nuclear pore complex protein Nup160
UniProt Protein Name:Nuclear pore complex protein Nup160
UniProt Synonym Protein Names:160 kDa nucleoporin; Nucleoporin Nup160
Protein Family:Nuclear pore complex protein
UniProt Gene Name:NUP160  
UniProt Entry Name:NU160_HUMAN
Anti-NUP160 Antibody (CAB13080)Western blot analysis of extracts of various cell lines, using NUP160 antibody (CAB13080) at 1:3000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 180s.
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