Anti-NUP153 Antibody (CAB8970)
- SKU:
- CAB8970
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- NUP153
- Synonyms:
- HNUP153
- Synonyms:
- N153
Description
| Product Name: | NUP153 Rabbit pAb |
| Product Code: | CAB8970 |
| Size: | 100uL |
| Synonyms: | NUP153, HNUP153, N153 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide of human NUP153 |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse liver, Rat liver |
| Immunogen: | A synthetic peptide of human NUP153 |
| Purification Method: | Affinity purification |
| Storage: | Store at 4°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 9972 |
| Uniprot: | P49790 |
| Cellular Location: | Nucleus, Nucleus membrane, nuclear pore complex |
| Calculated MW: | 149kDa/153kDa/157kDa |
| Observed MW: | 154KDa |
| UniProt Protein Function: | NUP153: Possible DNA-binding subunit of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. |
| UniProt Protein Details: | Protein type:Nuclear export; Nucleoporin Chromosomal Location of Human Ortholog: 6p22.3 Cellular Component: cytoplasm; nuclear inclusion body; nuclear membrane; nuclear pore; nucleolus; nucleoplasm Molecular Function:identical protein binding; nucleocytoplasmic transporter activity; protein anchor; protein binding; structural constituent of nuclear pore Biological Process: mitotic nuclear envelope disassembly; mRNA export from nucleus; negative regulation of RNA export from nucleus; nuclear pore complex assembly; protein sumoylation; RNA-mediated gene silencing; tRNA export from nucleus; viral reproduction; viral transcription |
| NCBI Summary: | Nuclear pore complexes regulate the transport of macromolecules between the nucleus and cytoplasm. They are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are glycoproteins found in nuclear pores and contain characteristic pentapeptide XFXFG repeats as well as O-linked N-acetylglucosamine residues oriented towards the cytoplasm. The protein encoded by this gene has three distinct domains: a N-terminal region containing a pore targeting and an RNA-binding domain domain, a central region containing multiple zinc finger motifs, and a C-terminal region containing multiple XFXFG repeats. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013] |
| UniProt Code: | P49790 |
| NCBI GenInfo Identifier: | 206729891 |
| NCBI Gene ID: | 9972 |
| NCBI Accession: | P49790.2 |
| UniProt Secondary Accession: | P49790,Q4LE47, Q5T9I7, Q7Z743, B4DIK2, E7EPX5, F6QR24 |
| UniProt Related Accession: | P49790 |
| Molecular Weight: | 157,338 Da |
| NCBI Full Name: | Nuclear pore complex protein Nup153 |
| NCBI Synonym Full Names: | nucleoporin 153 |
| NCBI Official Symbol: | NUP153 |
| NCBI Official Synonym Symbols: | N153; HNUP153 |
| NCBI Protein Information: | nuclear pore complex protein Nup153 |
| UniProt Protein Name: | Nuclear pore complex protein Nup153 |
| UniProt Synonym Protein Names: | 153 kDa nucleoporin; Nucleoporin Nup153 |
| Protein Family: | Nuclear pore complex protein |
| UniProt Gene Name: | NUP153 |
| UniProt Entry Name: | NU153_HUMAN |
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