Cell Biology Antibodies 5

Anti-NUDT6 Antibody (CAB14503)

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SKU:
CAB14503
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-NUDT6 Antibody
Antibody SKU:CAB14503
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 121-316 of human NUDT6 (NP_009014.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 121-316 of human NUDT6 (NP_009014.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:DSST LTLW LREG PSRL PGYA SHQV GVAG AVFD ESTR KILV VQDR NKLK NMWK FPGG LSEP EEDI GDTA VREV FEET GIKS EFRS VLSI RQQH TNPG AFGK SDMY IICR LKPY SFTI NFCQ EECL RCEW MDLN DLAK TENT TPIT SRVA RLLL YGYR EGFD KIDL TVEE LPAV YTGL FYKL YHKE LPEN YKTM KGID
Gene ID:11162
Uniprot:P53370
Cellular Location:Cytoplasm, Mitochondrion, Nucleus
Calculated MW:17kDa/35kDa
Observed MW:Refer to Figures
Synonyms:NUDT6, ASFGF2, FGF-AS, FGF2AS, GFG-1, GFG1
Background:This gene overlaps and lies on the opposite strand from FGF2 gene, and is thought to be the FGF2 antisense gene. The two genes are independently transcribed, and their expression shows an inverse relationship, suggesting that this antisense transcript may regulate FGF2 expression. This gene has also been shown to have hormone-regulatory and antiproliferative actions in the pituitary that are independent of FGF2 expression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:NUDT6: May contribute to the regulation of cell proliferation. Belongs to the Nudix hydrolase family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 4q26

Cellular Component: mitochondrion; nucleus

Molecular Function:growth factor activity; hydrolase activity

Biological Process: metabolic process

NCBI Summary:This gene overlaps and lies on the opposite strand from FGF2 gene, and is thought to be the FGF2 antisense gene. The two genes are independently transcribed, and their expression shows an inverse relationship, suggesting that this antisense transcript may regulate FGF2 expression. This gene has also been shown to have hormone-regulatory and antiproliferative actions in the pituitary that are independent of FGF2 expression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
UniProt Code:P53370
NCBI GenInfo Identifier:17380446
NCBI Gene ID:11162
NCBI Accession:P53370.2
UniProt Secondary Accession:P53370,O95097, Q9UQD9, A8K756,
UniProt Related Accession:P53370
Molecular Weight:316
NCBI Full Name:Nucleoside diphosphate-linked moiety X motif 6
NCBI Synonym Full Names:nudix (nucleoside diphosphate linked moiety X)-type motif 6
NCBI Official Symbol:NUDT6  
NCBI Official Synonym Symbols:GFG1; GFG-1; ASFGF2; FGF-AS; FGF2AS  
NCBI Protein Information:nucleoside diphosphate-linked moiety X motif 6; antisense basic fibroblast growth factor
UniProt Protein Name:Nucleoside diphosphate-linked moiety X motif 6
UniProt Synonym Protein Names:Antisense basic fibroblast growth factor; Protein GFG
Protein Family:Nudix hydrolase
UniProt Gene Name:NUDT6  
UniProt Entry Name:NUDT6_HUMAN
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