Cell Biology Antibodies 15
Anti-NUDT16 Antibody (CAB17825)
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- SKU:
- CAB17825
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-NUDT16 Antibody |
| Antibody SKU: | CAB17825 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-130 of human NUDT16 (NP_689608.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | 293T, A-549 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-130 of human NUDT16 (NP_689608.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | GFVD TQDR SLED GLNR ELRE ELGE AAAA FRVE RTDY RSSH VGSG PRVV AHFY AKRL TLEE LLAV EAGA TRA |
| Gene ID: | 131870 |
| Uniprot: | Q96DE0 |
| Cellular Location: | |
| Calculated MW: | 17kDa/21kDa/25kDa |
| Observed MW: | 21kDa |
 | Western blot - NUDT16 Polyclonal Antibody (CAB17825) |
| Synonyms: | NUDT16 |
| Background: |
| UniProt Protein Function: | NUDT16: RNA-decapping enzyme that binds specifically to U8 snoRNA. Part of the U8 snoRNP complex that is required for the accumulation of mature 5.8S and 28S rRNA. Has diphosphatase activity and removes m7G and m227G caps from U8 snoRNA. Has broad substrate specificity with manganese or cobalt as cofactor and can act on various RNA species (in vitro). Belongs to the Nudix hydrolase family. |
| UniProt Protein Details: | Protein type:EC 3.6.1.62; Nucleolus; Hydrolase Chromosomal Location of Human Ortholog: 3q22.1 Cellular Component: nucleoplasm; cytoplasm; nucleolus; nucleus Molecular Function:mRNA binding; snoRNA binding; m7G(5')pppN diphosphatase activity; protein homodimerization activity; metalloexopeptidase activity; GTP binding; manganese ion binding; magnesium ion binding; cobalt ion binding Biological Process: snoRNA catabolic process; dephosphorylation; nucleobase, nucleoside and nucleotide metabolic process; positive regulation of cell proliferation; mRNA catabolic process; proteolysis; adenosine to inosine editing; IDP catabolic process |
| UniProt Code: | Q96DE0 |
| NCBI GenInfo Identifier: | 73909074 |
| NCBI Gene ID: | 131870 |
| NCBI Accession: | AAH31215.2 |
| UniProt Secondary Accession: | Q96DE0,Q96N82, B4E3B4, E9PED4, F5GYJ1, |
| UniProt Related Accession: | Q96DE0 |
| Molecular Weight: | |
| NCBI Full Name: | NUDT16 protein |
| NCBI Synonym Full Names: | nudix (nucleoside diphosphate linked moiety X)-type motif 16 |
| NCBI Official Symbol: | NUDT16 |
| NCBI Protein Information: | U8 snoRNA-decapping enzyme |
| UniProt Protein Name: | U8 snoRNA-decapping enzyme |
| UniProt Synonym Protein Names: | IDP phosphatase (EC:3.6.1.-); IDPase; Inosine diphosphate phosphatase; Nucleoside diphosphate-linked moiety X motif 16; Nudix motif 16; U8 snoRNA-binding protein H29K; m7GpppN-mRNA hydrolase |
| Protein Family: | Nudix hydrolase |
| UniProt Gene Name: | NUDT16 |
| UniProt Entry Name: | NUD16_HUMAN |
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