Cell Biology Antibodies 4
Anti-NTN4 Antibody (CAB13775)
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- SKU:
- CAB13775
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-NTN4 Antibody |
| Antibody SKU: | CAB13775 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 290-520 of human NTN4 (NP_067052.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | A-549, Mouse kidney, Rat heart |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 290-520 of human NTN4 (NP_067052.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | HGKC MCKH NTAG SHCQ HCAP LYND RPWE AADG KTGA PNEC RTCK CNGH ADTC HFDV NVWE ASGN RSGG VCDD CQHN TEGQ YCQR CKPG FYRD LRRP FSAP DACK PCSC HPVG SAVL PANS VTFC DPSN GDCP CKPG VAGR RCDR CMVG YWGF GDYG CRPC DCAG SCDP ITGD CISS HTDI DWYH EVPD FRPV HNKS EPAW EWED AQGF SALL HSGK CECK EQTL GNAK AFC |
| Gene ID: | 59277 |
| Uniprot: | Q9HB63 |
| Cellular Location: | Secreted, basement membrane, extracellular matrix, extracellular space |
| Calculated MW: | 66kDa/67kDa/70kDa |
| Observed MW: | 70kDa |
| Synonyms: | NTN4, PRO3091, netrin-4 |
| Background: | This gene encodes a member of the netrin family of proteins, which function in various biological processes including axon guidance, tumorogenesis, and angiogenesis. Netrins are laminin-related proteins that have an N-terminal laminin-type domain, epidermal growth factor-like repeat domain, and a positively charged heparin-binding domain at the C-terminus. The protein encoded by this gene is involved in processes including neurite growth and migration, angiogenesis and mural cell adhesion to endothelial cells. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | May play an important role in neural, kidney and vascular development. Promotes neurite elongation from olfactory bulb explants. |
| NCBI Summary: | This gene encodes a member of the netrin family of proteins, which function in various biological processes including axon guidance, tumorogenesis, and angiogenesis. Netrins are laminin-related proteins that have an N-terminal laminin-type domain, epidermal growth factor-like repeat domain, and a positively charged heparin-binding domain at the C-terminus. The protein encoded by this gene is involved in processes including neurite growth and migration, angiogenesis and mural cell adhesion to endothelial cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016] |
| UniProt Code: | Q9HB63 |
| NCBI GenInfo Identifier: | 1046552696 |
| NCBI Gene ID: | 59277 |
| NCBI Accession: | NP_001316629.1 |
| UniProt Secondary Accession: | Q9HB63,Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44 Q9P133, B2RNC2, |
| UniProt Related Accession: | Q9HB63 |
| Molecular Weight: | 66,352 Da |
| NCBI Full Name: | netrin-4 isoform 2 |
| NCBI Synonym Full Names: | netrin 4 |
| NCBI Official Symbol: | NTN4 |
| NCBI Official Synonym Symbols: | PRO3091 |
| NCBI Protein Information: | netrin-4 |
| UniProt Protein Name: | Netrin-4 |
| UniProt Synonym Protein Names: | Beta-netrin; Hepar-derived netrin-like protein |
| Protein Family: | Netrin |
| UniProt Gene Name: | NTN4 |
 | Western blot analysis of extracts of various cell lines, using NTN4 antibody (CAB13775) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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