Cell Biology Antibodies 15
Anti-NSUN5 Antibody (CAB5992)
- SKU:
- CAB5992
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-NSUN5 Antibody |
Antibody SKU: | CAB5992 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 277-466 of human NSUN5 (NP_683759.1). |
Application: | WB IHC |
Recommended Dilution: | WB 1:200 - 1:2000 IHC 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | HepG2, RD, Rat brain |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 277-466 of human NSUN5 (NP_683759.1). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | SCCE LAEE DFLA VSPS DPRY HEVH YILL DPSC SGSG MPSR QLEE PGAG TPSP VRLH ALAG FQQR ALCH ALTF PSLQ RLVY STCS LCQE ENED VVRD ALQQ NPGA FRLA PALP AWPH RGLS TFPG AEHC LRAS PETT LSSG FFVA VIER VEVP SSAS QAKA SAPE RTPS PAPK RKKR QQRA AAGA CTPP CT |
Gene ID: | 55695 |
Uniprot: | Q96P11 |
Cellular Location: | |
Calculated MW: | 36kDa/42kDa/46kDa/50kDa/51kDa |
Observed MW: | 47kDa |
Synonyms: | NSUN5, NOL1, NOL1R, NSUN5A, WBSCR20, WBSCR20A, p120, p120(NOL1) |
Background: | This gene encodes a member of an evolutionarily conserved family of proteins that may function as methyltransferases. This gene is located in a larger region of chromosome 7 that is deleted in Williams-Beuren syndrome, a multisystem developmental disorder. There are two pseudogenes for this gene located in the same region of chromosome 7. Alternative splicing results in multiple transcript variants encoding different isoforms. |
UniProt Protein Function: | S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 3782 in 28S rRNA. |
NCBI Summary: | This gene encodes a member of an evolutionarily conserved family of proteins that may function as methyltransferases. This gene is located in a larger region of chromosome 7 that is deleted in Williams-Beuren syndrome, a multisystem developmental disorder. There are two pseudogenes for this gene located in the same region of chromosome 7. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013] |
UniProt Code: | Q96P11 |
NCBI GenInfo Identifier: | 270288816 |
NCBI Gene ID: | 55695 |
NCBI Accession: | NP_001161819.1 |
UniProt Related Accession: | Q96P11 |
Molecular Weight: | |
NCBI Full Name: | probable 28S rRNA (cytosine-C(5))-methyltransferase isoform 3 |
NCBI Synonym Full Names: | NOP2/Sun RNA methyltransferase 5 |
NCBI Official Symbol: | NSUN5 |
NCBI Official Synonym Symbols: | NOL1; p120; NOL1R; NSUN5A; WBSCR20; WBSCR20A; p120(NOL1) |
NCBI Protein Information: | probable 28S rRNA (cytosine-C(5))-methyltransferase |
UniProt Protein Name: | Probable 28S rRNA (cytosine-C(5))-methyltransferase |
UniProt Synonym Protein Names: | NOL1-related protein; NOL1R; NOL1/NOP2/Sun domain family member 5; Williams-Beuren syndrome chromosomal region 20A protein |
UniProt Gene Name: | NSUN5 |
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