Cell Biology Antibodies 14
Anti-NRL Antibody (CAB16935)
(No reviews yet)
Write a Review
- SKU:
- CAB16935
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-NRL Antibody |
| Antibody SKU: | CAB16935 |
| Antibody Size: | 20uL, 50 uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide of human NRL. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: |
| Immunogen: | A synthetic peptide of human NRL. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 4901 |
| Uniprot: | P54845 |
| Cellular Location: | |
| Calculated MW: | 11kDa/25kDa |
| Observed MW: | Refer to figures |
| Synonyms: | NRL, D14S46E, NRL-MAF, RP27 |
| Background: | This gene encodes a basic motif-leucine zipper transcription factor of the Maf subfamily. The encoded protein is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function. Mutations in this gene have been associated with retinitis pigmentosa and retinal degenerative diseases. |
| UniProt Protein Function: | Acts as a transcriptional activator which regulates the expression of several rod-specific genes, including RHO and PDE6B (PubMed:21981118). Functions also as a transcriptional coactivator, stimulating transcription mediated by the transcription factor CRX and NR2E3 (PubMed:17335001). Binds in a sequence-specific manner to the rhodopsin promoter (PubMed:17335001). |
| NCBI Summary: | This gene encodes a basic motif-leucine zipper transcription factor of the Maf subfamily. The encoded protein is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function. Mutations in this gene have been associated with retinitis pigmentosa and retinal degenerative diseases. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P54845 |
| NCBI GenInfo Identifier: | 5453802 |
| NCBI Gene ID: | 4901 |
| NCBI Accession: | NP_006168.1 |
| UniProt Secondary Accession: | P54845,Q53XD0, A8MX14, |
| UniProt Related Accession: | P54845 |
| Molecular Weight: | 11,276 Da |
| NCBI Full Name: | neural retina-specific leucine zipper protein isoform 1 |
| NCBI Synonym Full Names: | neural retina leucine zipper |
| NCBI Official Symbol: | NRL |
| NCBI Official Synonym Symbols: | RP27; D14S46E; NRL-MAF |
| NCBI Protein Information: | neural retina-specific leucine zipper protein |
| UniProt Protein Name: | Neural retina-specific leucine zipper protein |
| Protein Family: | Neural retina-specific leucine zipper protein |
| UniProt Gene Name: | NRL |
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
