Cell Biology Antibodies 14

Anti-NRL Antibody (CAB16935)

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SKU:
CAB16935
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-NRL Antibody
Antibody SKU:CAB16935
Antibody Size:20uL, 50 uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide of human NRL.
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:
Immunogen:A synthetic peptide of human NRL.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:4901
Uniprot:P54845
Cellular Location:
Calculated MW:11kDa/25kDa
Observed MW:Refer to figures
Synonyms:NRL, D14S46E, NRL-MAF, RP27
Background:This gene encodes a basic motif-leucine zipper transcription factor of the Maf subfamily. The encoded protein is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function. Mutations in this gene have been associated with retinitis pigmentosa and retinal degenerative diseases.
UniProt Protein Function:Acts as a transcriptional activator which regulates the expression of several rod-specific genes, including RHO and PDE6B (PubMed:21981118). Functions also as a transcriptional coactivator, stimulating transcription mediated by the transcription factor CRX and NR2E3 (PubMed:17335001). Binds in a sequence-specific manner to the rhodopsin promoter (PubMed:17335001).
NCBI Summary:This gene encodes a basic motif-leucine zipper transcription factor of the Maf subfamily. The encoded protein is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function. Mutations in this gene have been associated with retinitis pigmentosa and retinal degenerative diseases. [provided by RefSeq, Jul 2008]
UniProt Code:P54845
NCBI GenInfo Identifier:5453802
NCBI Gene ID:4901
NCBI Accession:NP_006168.1
UniProt Secondary Accession:P54845,Q53XD0, A8MX14,
UniProt Related Accession:P54845
Molecular Weight:11,276 Da
NCBI Full Name:neural retina-specific leucine zipper protein isoform 1
NCBI Synonym Full Names:neural retina leucine zipper
NCBI Official Symbol:NRL  
NCBI Official Synonym Symbols:RP27; D14S46E; NRL-MAF  
NCBI Protein Information:neural retina-specific leucine zipper protein
UniProt Protein Name:Neural retina-specific leucine zipper protein
Protein Family:Neural retina-specific leucine zipper protein
UniProt Gene Name:NRL  
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