Cell Biology Antibodies 1

Anti-NRBP1 Antibody (CAB10301)

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SKU:
CAB10301
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-NRBP1 Antibody
Antibody SKU:CAB10301
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 406-535 of human NRBP1 (NP_037524.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:Jurkat, MCF7, Mouse brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 406-535 of human NRBP1 (NP_037524.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:AFGL PRPQ QPQQ EEVT SPVV PPSV KTPT PEPA EVET RKVV LMQC NIES VEEG VKHH LTLL LKLE DKLN RHLS CDLM PNEN IPEL AAEL VQLG FISE ADQS RLTS LLEE TLNK FNFA RNST LNSA AVTV SS
Gene ID:29959
Uniprot:Q9UHY1
Cellular Location:Cell projection, Cytoplasm, Endomembrane system, cell cortex, lamellipodium
Calculated MW:59kDa
Observed MW:60kDa
Synonyms:NRBP1, BCON3, MADM, MUDPNP, NRBP
Background:
UniProt Protein Function:NRBP1: May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
UniProt Protein Details:

Protein type:Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, Other; Other group; NRBP family

Chromosomal Location of Human Ortholog: 2p23

Cellular Component: cell cortex; endomembrane system; lamellipodium; membrane; nucleoplasm; perinuclear region of cytoplasm

Molecular Function:ATP binding; protein binding; protein homodimerization activity; protein kinase activity

Biological Process: ER to Golgi vesicle-mediated transport; gene expression; protein amino acid phosphorylation; transcription initiation from RNA polymerase II promoter

UniProt Code:Q9UHY1
NCBI GenInfo Identifier:74761962
NCBI Gene ID:29959
NCBI Accession:Q9UHY1.1
UniProt Secondary Accession:Q9UHY1,Q53FZ5, Q96SU3, B3KV40, D6W558,
UniProt Related Accession:Q9UHY1
Molecular Weight:59,845 Da
NCBI Full Name:Nuclear receptor-binding protein
NCBI Synonym Full Names:nuclear receptor binding protein 1
NCBI Official Symbol:NRBP1  
NCBI Official Synonym Symbols:MADM; NRBP; BCON3; MUDPNP  
NCBI Protein Information:nuclear receptor-binding protein
UniProt Protein Name:Nuclear receptor-binding protein
Protein Family:Nuclear receptor-binding protein
UniProt Gene Name:NRBP1  
UniProt Entry Name:NRBP_HUMAN
Anti-NRBP1 Antibody (CAB10301)Western blot analysis of extracts of various cell lines, using NRBP1 antibody (CAB10301) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
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