KO Validated Antibodies 2

Anti-NRBF2 Antibody (CAB19856)[KO Validated]

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SKU:
CAB19856
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Autophagy

Description

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Antibody Name:Anti-NRBF2 Antibody [KO Validated]
Antibody SKU:CAB19856
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human NRBF2.
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:10 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa
Immunogen:Recombinant protein of human NRBF2.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:29982
Uniprot:Q96F24
Cellular Location:Cytoplasm, Cytoplasmic vesicle, Nucleus, autophagosome
Calculated MW:26kDa/31kDa/32kDa
Observed MW:40KDa
Anti-NRBF2 Antibody [KO Validated] (CAB19856)Western blot analysis of extracts from normal (control) and NRBF2 knockout (KO) HeLa cells, using NRBF2 antibody (CAB19856) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
Synonyms:NRBF2, COPR, COPR1, COPR2, NRBF-2
Background:
UniProt Protein Function:NRBF2: May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro). Interacts with PPARA, PPARD and PPARG. Interacts with RARA, RARG and RXRA in the presence of bound ligand. Detected in keratinocytes, liver and placenta. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Transcription, coactivator/corepressor; Autophagy; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 10q21.3

Cellular Component: nucleoplasm; cytoplasm

Biological Process: transcription initiation from RNA polymerase II promoter; regulation of transcription, DNA-dependent; gene expression

UniProt Code:Q96F24
NCBI GenInfo Identifier:74731648
NCBI Gene ID:29982
NCBI Accession:Q96F24.1
UniProt Secondary Accession:Q96F24,Q86UR2, Q96NP6, Q9H0S9, Q9H2I2, A6PW36, B4DWS0
UniProt Related Accession:Q96F24
Molecular Weight:287
NCBI Full Name:Nuclear receptor-binding factor 2
NCBI Synonym Full Names:nuclear receptor binding factor 2
NCBI Official Symbol:NRBF2  
NCBI Official Synonym Symbols:COPR1; COPR2; NRBF-2  
NCBI Protein Information:nuclear receptor-binding factor 2; comodulator of PPAR and RXR 1; comodulator of PPAR and RXR 2; nuclear receptor binding factor-2
UniProt Protein Name:Nuclear receptor-binding factor 2
UniProt Synonym Protein Names:Comodulator of PPAR and RXR
Protein Family:Nuclear receptor-binding factor
UniProt Gene Name:NRBF2  
UniProt Entry Name:NRBF2_HUMAN
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