Name: Anti-NQO2 Antibody (CAB3846)
Brand: Cell Biology Antibodies 17
SKU: CAB3846
Availability: OutOfStock

Antibody Name:	Anti-NQO2 Antibody
Antibody SKU:	CAB3846
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	A synthesized peptide derived from human NQO2

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Human, Mouse, Rat
Positive Samples:	Mouse liver, Mouse kidney, Mouse thymus, Rat kidney

Immunogen:	A synthesized peptide derived from human NQO2
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	Email for sequence
Gene ID:	4835
Uniprot:	P16083
Cellular Location:
Calculated MW:	26kDa
Observed MW:	26KDa

Synonyms:

DHQV, DIA6, NMOR2, QR2

Background:

This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

UniProt Protein Function:	NQO2: The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. Belongs to the NAD(P)H dehydrogenase (quinone) family.
UniProt Protein Details:	Protein type:Oxidoreductase; EC 1.10.99.2 Chromosomal Location of Human Ortholog: 6p25.2 Cellular Component: nucleoplasm; cytoplasm Molecular Function:electron carrier activity; dihydronicotinamide riboside quinone reductase activity; NADPH dehydrogenase (quinone) activity; metal ion binding Biological Process: memory Disease: Breast Cancer
NCBI Summary:	This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
UniProt Code:	P16083
NCBI GenInfo Identifier:	317373581
NCBI Gene ID:	4835
NCBI Accession:	P16083.5
UniProt Secondary Accession:	P16083,Q9JI75,
UniProt Related Accession:	P16083
Molecular Weight:	231
NCBI Full Name:	Ribosyldihydronicotinamide dehydrogenase
NCBI Synonym Full Names:	NAD(P)H dehydrogenase, quinone 2
NCBI Official Symbol:	NQO2
NCBI Official Synonym Symbols:	QR2; DHQV; DIA6; NMOR2
NCBI Protein Information:	ribosyldihydronicotinamide dehydrogenase [quinone]; ribosyldihydronicotinamide dehydrogenase [quinone]; quinone reductase 2; NRH:quinone oxidoreductase 2; NAD(P)H menadione oxidoreductase-1, dioxin-inducible-2
UniProt Protein Name:	Ribosyldihydronicotinamide dehydrogenase [quinone]
UniProt Synonym Protein Names:	NRH dehydrogenase [quinone] 2; NRH:quinone oxidoreductase 2; Quinone reductase 2; QR2
Protein Family:	NADH-quinone oxidoreductase
UniProt Gene Name:	NQO2
UniProt Entry Name:	NQO2_HUMAN