Cell Biology Antibodies 17

Anti-NQO2 Antibody (CAB3846)

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SKU:
CAB3846
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-NQO2 Antibody
Antibody SKU:CAB3846
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human NQO2
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse liver, Mouse kidney, Mouse thymus, Rat kidney
Immunogen:A synthesized peptide derived from human NQO2
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:4835
Uniprot:P16083
Cellular Location:
Calculated MW:26kDa
Observed MW:26KDa
Synonyms:DHQV, DIA6, NMOR2, QR2
Background:This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
UniProt Protein Function:NQO2: The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. Belongs to the NAD(P)H dehydrogenase (quinone) family.
UniProt Protein Details:

Protein type:Oxidoreductase; EC 1.10.99.2

Chromosomal Location of Human Ortholog: 6p25.2

Cellular Component: nucleoplasm; cytoplasm

Molecular Function:electron carrier activity; dihydronicotinamide riboside quinone reductase activity; NADPH dehydrogenase (quinone) activity; metal ion binding

Biological Process: memory

Disease: Breast Cancer

NCBI Summary:This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
UniProt Code:P16083
NCBI GenInfo Identifier:317373581
NCBI Gene ID:4835
NCBI Accession:P16083.5
UniProt Secondary Accession:P16083,Q9JI75,
UniProt Related Accession:P16083
Molecular Weight:231
NCBI Full Name:Ribosyldihydronicotinamide dehydrogenase
NCBI Synonym Full Names:NAD(P)H dehydrogenase, quinone 2
NCBI Official Symbol:NQO2  
NCBI Official Synonym Symbols:QR2; DHQV; DIA6; NMOR2  
NCBI Protein Information:ribosyldihydronicotinamide dehydrogenase [quinone]; ribosyldihydronicotinamide dehydrogenase [quinone]; quinone reductase 2; NRH:quinone oxidoreductase 2; NAD(P)H menadione oxidoreductase-1, dioxin-inducible-2
UniProt Protein Name:Ribosyldihydronicotinamide dehydrogenase [quinone]
UniProt Synonym Protein Names:NRH dehydrogenase [quinone] 2; NRH:quinone oxidoreductase 2; Quinone reductase 2; QR2
Protein Family:NADH-quinone oxidoreductase
UniProt Gene Name:NQO2  
UniProt Entry Name:NQO2_HUMAN
Anti-NQO2 Antibody (CAB3846)Western blot - NQO2 Rabbit mAb (CAB3846)
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