Description
Product Name: | NPY5R Rabbit pAb |
Product Code: | CAB20207 |
Size: | 50uL, 100uL |
Synonyms: | NPYR5, NPY5-R, NPYY5-R |
Applications: | WB |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human NPY5R (NP_001304020.1). |
Applications: | WB |
Recommended Dilutions: | WB 1:500 - 1:2000 |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human NPY5R (NP_001304020.1). |
Purification Method: | Affinity purification |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 4889 |
Uniprot: | Q15761 |
Calculated MW: | 51kDa |
Observed MW: | Refer to figures |
UniProt Protein Function: | NPY5R: Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders. Belongs to the G-protein coupled receptor 1 family. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCR Chromosomal Location of Human Ortholog: 4q31-q32 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:neuropeptide Y receptor activity Biological Process: cell surface receptor linked signal transduction; feeding behavior; G-protein coupled receptor protein signaling pathway; synaptic transmission |
NCBI Summary: | The protein encoded by this gene is a receptor for neuropeptide Y and peptide YY. The encoded protein appears to be involved in regulating food intake, with defects in this gene being associated with eating disorders. Also, the encoded protein is involved in a pathway that protects neuroblastoma cells from chemotherapy-induced cell death, providing a possible therapeutic target against neuroblastoma. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2015] |
UniProt Code: | Q15761 |
NCBI GenInfo Identifier: | 215274093 |
NCBI Gene ID: | 4889 |
NCBI Accession: | Q15761.2 |
UniProt Secondary Accession: | Q15761,Q6GTR7, Q92916, |
UniProt Related Accession: | Q15761 |
Molecular Weight: | 50,727 Da |
NCBI Full Name: | Neuropeptide Y receptor type 5 |
NCBI Synonym Full Names: | neuropeptide Y receptor Y5 |
NCBI Official Symbol: | NPY5R |
NCBI Official Synonym Symbols: | NPYR5; NPY5-R; NPYY5-R |
NCBI Protein Information: | neuropeptide Y receptor type 5 |
UniProt Protein Name: | Neuropeptide Y receptor type 5 |
UniProt Synonym Protein Names: | NPY-Y5 receptor; NPYY5-R; Y5 receptor |
Protein Family: | Neuropeptide Y receptor |
UniProt Gene Name: | NPY5R |
UniProt Entry Name: | NPY5R_HUMAN |