Cell Biology Antibodies 11

Anti-NPY4R Antibody (CAB8143)

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SKU:
CAB8143
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:NPY4R Rabbit Polyclonal Antibody
Antibody SKU:CAB8143
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human NPY4R (NP_005963.4).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:MCF7, SH-SY5Y, SW480, HT-29
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human NPY4R (NP_005963.4).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MNTS HLLA LLLP KSPQ GENR SKPL GTPY NFSE HCQD SVDV MVFI VTSY SIET VVGV LGNL CLMC VTVR QKEK ANVT NLLI
Gene ID:5540
Uniprot:P50391
Cellular Location:Cell membrane, Multi-pass membrane protein
Calculated MW:42kDa
Observed MW:42kDa
Synonyms:NPY4R, NPY4-R, PP1, PPYR1, Y4
Background:
UniProt Protein Function:NPY4R: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PP, PP (2-36) and [Ile-31, Gln-34] PP > [Pro-34] PYY > PYY and [Leu-31, Pro-34] NPY > NPY > PYY (3-36) and NPY (2-36) > PP (13- 36) > PP (31-36) > NPY free acid. Belongs to the G-protein coupled receptor 1 family.
UniProt Protein Details:

Protein type:Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1

Chromosomal Location of Human Ortholog: 10q11.2

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function:G-protein coupled receptor activity; pancreatic polypeptide receptor activity

Biological Process: blood circulation; cell surface receptor linked signal transduction; digestion; feeding behavior; G-protein coupled receptor protein signaling pathway; neuropeptide signaling pathway

UniProt Code:P50391
NCBI GenInfo Identifier:1709423
NCBI Gene ID:5540
NCBI Accession:P50391.1
UniProt Secondary Accession:P50391,Q13456, Q5ISU3, Q5T2X9, Q6FH06,
UniProt Related Accession:P50391
Molecular Weight:42,195 Da
NCBI Full Name:Neuropeptide Y receptor type 4
NCBI Synonym Full Names:neuropeptide Y receptor Y4
NCBI Official Symbol:NPY4R  
NCBI Official Synonym Symbols:Y4; PP1; PPYR1; NPY4-R  
NCBI Protein Information:neuropeptide Y receptor type 4
UniProt Protein Name:Neuropeptide Y receptor type 4
UniProt Synonym Protein Names:Pancreatic polypeptide receptor 1; PP1
Protein Family:Neuropeptide Y receptor
UniProt Gene Name:NPY4R  
UniProt Entry Name:NPY4R_HUMAN
Anti-NPY4R Polyclonal Antibody (CAB8143)Western blot analysis of extracts of various cell lines, using NPY4R antibody (CAB8143) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
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