Cell Biology Antibodies 11
Anti-NPY4R Antibody (CAB8143)
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- SKU:
- CAB8143
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | NPY4R Rabbit Polyclonal Antibody |
| Antibody SKU: | CAB8143 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human NPY4R (NP_005963.4). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | MCF7, SH-SY5Y, SW480, HT-29 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human NPY4R (NP_005963.4). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MNTS HLLA LLLP KSPQ GENR SKPL GTPY NFSE HCQD SVDV MVFI VTSY SIET VVGV LGNL CLMC VTVR QKEK ANVT NLLI |
| Gene ID: | 5540 |
| Uniprot: | P50391 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 42kDa |
| Observed MW: | 42kDa |
| Synonyms: | NPY4R, NPY4-R, PP1, PPYR1, Y4 |
| Background: |
| UniProt Protein Function: | NPY4R: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PP, PP (2-36) and [Ile-31, Gln-34] PP > [Pro-34] PYY > PYY and [Leu-31, Pro-34] NPY > NPY > PYY (3-36) and NPY (2-36) > PP (13- 36) > PP (31-36) > NPY free acid. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1 Chromosomal Location of Human Ortholog: 10q11.2 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:G-protein coupled receptor activity; pancreatic polypeptide receptor activity Biological Process: blood circulation; cell surface receptor linked signal transduction; digestion; feeding behavior; G-protein coupled receptor protein signaling pathway; neuropeptide signaling pathway |
| UniProt Code: | P50391 |
| NCBI GenInfo Identifier: | 1709423 |
| NCBI Gene ID: | 5540 |
| NCBI Accession: | P50391.1 |
| UniProt Secondary Accession: | P50391,Q13456, Q5ISU3, Q5T2X9, Q6FH06, |
| UniProt Related Accession: | P50391 |
| Molecular Weight: | 42,195 Da |
| NCBI Full Name: | Neuropeptide Y receptor type 4 |
| NCBI Synonym Full Names: | neuropeptide Y receptor Y4 |
| NCBI Official Symbol: | NPY4R |
| NCBI Official Synonym Symbols: | Y4; PP1; PPYR1; NPY4-R |
| NCBI Protein Information: | neuropeptide Y receptor type 4 |
| UniProt Protein Name: | Neuropeptide Y receptor type 4 |
| UniProt Synonym Protein Names: | Pancreatic polypeptide receptor 1; PP1 |
| Protein Family: | Neuropeptide Y receptor |
| UniProt Gene Name: | NPY4R |
| UniProt Entry Name: | NPY4R_HUMAN |
 | Western blot analysis of extracts of various cell lines, using NPY4R antibody (CAB8143) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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