Cell Biology Antibodies 9

Anti-NOV Antibody (CAB5320)

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SKU:
CAB5320
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-NOV Antibody
Antibody SKU:CAB5320
Antibody Size:20uL, 50uL, 100uL
Application:IHC
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 32-357 of human NOV (NP_002505.1).
Application:IHC
Recommended Dilution:IHC 1:50 - 1:100
Reactivity:Human
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 32-357 of human NOV (NP_002505.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:TQRC PPQC PGRC PATP PTCA PGVR AVLD GCSC CLVC ARQR GESC SDLE PCDE SSGL YCDR SADP SNQT GICT AVEG DNCV FDGV IYRS GEKF QPSC KFQC TCRD GQIG CVPR CQLD VLLP EPNC PAPR KVEV PGEC CEKW ICGP DEED SLGG LTLA AYRP EATL GVEV SDSS VNCI EQTT EWTA CSKS CGMG FSTR VTNR NRQC EMLK QTRL CMVR PCEQ EPEQ PTDK KGKK CLRT KKSL KAIH LQFK NCTS LHTY KPRF CGVC SDGR CCTP HNTK TIQA EFQC SPGQ IVKK PVMV IGTC TCHT NCPK NNEA FLQE LELK TTRG KM
Gene ID:4856
Uniprot:P48745
Cellular Location:Cell junction, Cytoplasm, Secreted, gap junction
Calculated MW:39kDa
Observed MW:
Synonyms:NOV, CCN3, IBP-9, IGFBP-9, IGFBP9, NOVh
Background:The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development.
UniProt Protein Function:NOV: Immediate-early protein likely to play a role in cell growth regulation. Belongs to the CCN family. Expression is down-regulated by WT1. Interacts with FBLN1.
UniProt Protein Details:

Protein type:Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 8q24.1

Cellular Component: proteinaceous extracellular matrix; cell soma; intracellular membrane-bound organelle; axon; dendrite

Molecular Function:heparin binding; integrin binding; insulin-like growth factor binding; growth factor activity

Biological Process: cell-cell signaling; regulation of gene expression; regulation of cell growth; cell adhesion; signal transduction

NCBI Summary:The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development. [provided by RefSeq, Feb 2009]
UniProt Code:P48745
NCBI GenInfo Identifier:1352515
NCBI Gene ID:4856
NCBI Accession:P48745.1
UniProt Secondary Accession:P48745,Q6I9S3, Q96BY5, Q9UDE4, B2R5X7,
UniProt Related Accession:P48745
Molecular Weight:39,162 Da
NCBI Full Name:Protein NOV homolog
NCBI Synonym Full Names:nephroblastoma overexpressed
NCBI Official Symbol:NOV  
NCBI Official Synonym Symbols:CCN3; NOVh; IBP-9; IGFBP9; IGFBP-9  
NCBI Protein Information:protein NOV homolog; CCN family member 3; IGF-binding protein 9; insulin-like growth factor-binding protein 9; nephroblastoma-overexpressed gene protein homolog
UniProt Protein Name:Protein NOV homolog
UniProt Synonym Protein Names:CCN family member 3; Insulin-like growth factor-binding protein 9; IBP-9; IGF-binding protein 9; IGFBP-9; Nephroblastoma-overexpressed gene protein homolog
Protein Family:Protein
UniProt Gene Name:NOV  
UniProt Entry Name:NOV_HUMAN
Anti-NOV Antibody (CAB5320)Immunohistochemistry of paraffin-embedded human prostate using NOV antibody (CAB5320) at dilution of 1:100 (40x lens).
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