Anti-NOP56 Antibody (CAB18693)
- SKU:
- CAB18693
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- NOL5A
- Synonyms:
- SCA36
- Research Area:
- Cell Biology
Description
| Product Name: | NOP56 Rabbit pAb |
| Product Code: | CAB18693 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | NOL5A, SCA36 |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human NOP56. |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | HeLa, HepG2, SH-SY5Y |
| Immunogen: | Recombinant protein of human NOP56. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 10528 |
| Uniprot: | O00567 |
| Cellular Location: | Cytoplasm, Nucleus, nucleolus, nucleoplasm |
| Calculated MW: | 66kDa |
| Observed MW: | 70KDa |
| UniProt Protein Function: | Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs. |
| NCBI Summary: | Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined. [provided by RefSeq, Jul 2016] |
| UniProt Code: | O00567 |
| NCBI GenInfo Identifier: | 32483374 |
| NCBI Gene ID: | 10528 |
| NCBI Accession: | NP_006383 |
| UniProt Related Accession: | O00567 |
| Molecular Weight: | 66kDa |
| NCBI Full Name: | nucleolar protein 56 |
| NCBI Synonym Full Names: | NOP56 ribonucleoprotein |
| NCBI Official Symbol: | NOP56 |
| NCBI Official Synonym Symbols: | NOL5A; SCA36 |
| NCBI Protein Information: | nucleolar protein 56 |
| UniProt Protein Name: | Nucleolar protein 56 |
| UniProt Synonym Protein Names: | Nucleolar protein 5A |
| Protein Family: | Nucleolar protein |
| UniProt Gene Name: | NOP56 |
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