Description
Product Name: | NOP2 Rabbit pAb |
Product Code: | CAB19421 |
Size: | 50uL, 100uL |
Synonyms: | NOP2, NOL1, NOP120, NSUN1, p120 |
Applications: | WB |
Reactivity: | Human, Mouse |
Host Species: | Rabbit |
Immunogen: | A synthetic peptide of human NOP2 |
Applications: | WB |
Recommended Dilutions: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse |
Positive Samples: | 293T, Jurkat, Mouse liver, Mouse thymus, Mouse placenta |
Immunogen: | A synthetic peptide of human NOP2 |
Purification Method: | Affinity purification |
Storage: | Store at 4°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 4839 |
Uniprot: | P46087 |
Cellular Location: | Nucleus, nucleolus |
Calculated MW: | 69kDa/88kDa/89kDa/92kDa |
Observed MW: | 110KDa |
UniProt Protein Function: | NOP2: May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. May act as ribosomal RNA methyltransferase. Belongs to the methyltransferase superfamily. RsmB/NOP family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cell cycle regulation; EC 2.1.1.-; Methyltransferase; Nucleolus; RNA-binding Chromosomal Location of Human Ortholog: 12p13.31 Cellular Component: nucleolus; nucleoplasm Molecular Function:protein binding; RNA binding; rRNA (cytosine-C5-967)-methyltransferase activity Biological Process: maturation of LSU-rRNA; positive regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter |
UniProt Code: | P46087 |
NCBI GenInfo Identifier: | 146289861 |
NCBI Gene ID: | 4839 |
NCBI Accession: | P46087.2 |
UniProt Secondary Accession: | P46087,Q05BA7, Q0P5S5, Q3KQS4, Q58F30, A1A4Z3, B3KPD6 |
UniProt Related Accession: | P46087 |
Molecular Weight: | 89kDa |
NCBI Full Name: | Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase |
NCBI Synonym Full Names: | NOP2 nucleolar protein |
NCBI Official Symbol: | NOP2 |
NCBI Official Synonym Symbols: | NOL1; p120; NSUN1; NOP120 |
NCBI Protein Information: | probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase |
UniProt Protein Name: | Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase |
UniProt Synonym Protein Names: | Nucleolar protein 1; Nucleolar protein 2 homolog; Proliferating-cell nucleolar antigen p120; Proliferation-associated nucleolar protein p120 |
Protein Family: | 25S rRNA |
UniProt Gene Name: | NOP2 |