Cell Biology Antibodies 3

Anti-NMUR2 Antibody (CAB12812)

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SKU:
CAB12812
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-NMUR2 Antibody
Antibody SKU:CAB12812
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 326-415 of human NMUR2 (NP_064552.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:SGC-7901, Mouse uterus, Mouse small intestine, Rat uterus
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 326-415 of human NMUR2 (NP_064552.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:IYNL LSRR FQAA FQNV ISSF HKQW HSQH DPQL PPAQ RNIF LTEC HFVE LTED IGPQ FPCQ SSMH NSHL PAAL SSEQ MSRT NYQS FHFN KT
Gene ID:56923
Uniprot:Q9GZQ4
Cellular Location:Cell membrane, Multi-pass membrane protein
Calculated MW:47kDa
Observed MW:48kDa
Synonyms:NMUR2, FM-4, FM4, NMU-R2, NMU2R, TGR-1, TGR1
Background:This gene encodes a protein from the G-protein coupled receptor 1 family. This protein is a receptor for neuromedin U, which is a neuropeptide that is widely distributed in the gut and central nervous system. This receptor plays an important role in the regulation of food intake and body weight.
UniProt Protein Function:NMUR2: Receptor for the neuromedin-U and neuromedin-S neuropeptides. Belongs to the G-protein coupled receptor 1 family.
UniProt Protein Details:

Protein type:GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 5q33.1

Cellular Component: integral to membrane; plasma membrane

Molecular Function:G-protein coupled receptor activity; GTP binding; intracellular calcium activated chloride channel activity; neuromedin U binding; neuromedin U receptor activity; protein binding

Biological Process: arachidonic acid secretion; calcium ion transport; calcium-dependent phospholipase A2 activation; cell-cell signaling; central nervous system development; elevation of cytosolic calcium ion concentration; feeding behavior; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); inositol phosphate-mediated signaling

NCBI Summary:This gene encodes a protein from the G-protein coupled receptor 1 family. This protein is a receptor for neuromedin U, which is a neuropeptide that is widely distributed in the gut and central nervous system. This receptor plays an important role in the regulation of food intake and body weight. [provided by RefSeq, Jul 2008]
UniProt Code:Q9GZQ4
NCBI GenInfo Identifier:311033403
NCBI Gene ID:56923
NCBI Accession:Q9GZQ4.2
UniProt Secondary Accession:Q9GZQ4,Q7LC54, Q96AM5, Q9NRA6,
UniProt Related Accession:Q9GZQ4
Molecular Weight:48kDa
NCBI Full Name:Neuromedin-U receptor 2
NCBI Synonym Full Names:neuromedin U receptor 2
NCBI Official Symbol:NMUR2  
NCBI Official Synonym Symbols:FM4; FM-4; TGR1; NMU2R; TGR-1; NMU-R2  
NCBI Protein Information:neuromedin-U receptor 2
UniProt Protein Name:Neuromedin-U receptor 2
UniProt Synonym Protein Names:G-protein coupled receptor FM-4; G-protein coupled receptor TGR-1
Protein Family:Neuromedin-U receptor
UniProt Gene Name:NMUR2  
Anti-NMUR2 Antibody (CAB12812)Western blot analysis of extracts of various cell lines, using NMUR2 antibody (CAB12812) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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