Metabolism Antibodies 1

Anti-NME7 Antibody (CAB14882)

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SKU:
CAB14882
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism

Description

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Antibody Name:Anti-NME7 Antibody
Antibody SKU:CAB14882
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-376 of human NME7 (NP_037462.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse spleen, Mouse testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-376 of human NME7 (NP_037462.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MNHS ERFV FIAE WYDP NASL LRRY ELLF YPGD GSVE MHDV KNHR TFLK RTKY DNLH LEDL FIGN KVNV FSRQ LVLI DYGD QYTA RQLG SRKE KTLA LIKP DAIS KAGE IIEI INKA GFTI TKLK MMML SRKE ALDF HVDH QSRP FFNE LIQF ITTG PIIA MEIL RDDA ICEW KRLL GPAN SGVA RTDA SESI RALF GTDG IRNA AHGP DSFA SAAR EMEL FFPS SGGC GPAN TAKF TNCT CCIV KPHA VSEG LLGK ILMA IRDA GFEI SAMQ MFNM DRVN VEEF YEVY KGVV TEYH DMVT EMYS GPCV AMEI QQNN ATKT FREF CGPA DPEI ARHL RPGT LRAI FGKT KIQN AVHC TDLP EDGL LEVQ YFFK ILDN
Gene ID:29922
Uniprot:Q9Y5B8
Cellular Location:
Calculated MW:38kDa/42kDa
Observed MW:39kDa
Synonyms:NME7, CFAP67, MN23H7, NDK 7, NDK7, nm23-H7
Background:This gene encodes a member of the non-metastatic expressed family of nucleoside diphosphate kinases. Members of this family are enzymes that catalyzes phosphate transfer from nucleoside triphosphates to nucleoside diphosphates. This protein contains two kinase domains, one of which is involved in autophosphorylation and the other may be inactive. This protein localizes to the centrosome and functions as a component of the gamma-tubulin ring complex which plays a role in microtubule organization. Mutations in this gene may be associated with venous thromboembolism. Alternate splicing results in multiple transcript variants.
UniProt Protein Function:NDK7: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Belongs to the NDK family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine; Kinase, other; Kinase, nucleoside diphosphate; EC 2.7.4.6; Other group; NDK family

Chromosomal Location of Human Ortholog: 1q24

Cellular Component: centrosome

Molecular Function:nucleoside diphosphate kinase activity; protein binding

UniProt Code:Q9Y5B8
NCBI GenInfo Identifier:12230353
NCBI Gene ID:29922
NCBI Accession:Q9Y5B8.1
UniProt Secondary Accession:Q9Y5B8,Q5TGZ4, A8K3T6, A8MY09, B3KSW9,
UniProt Related Accession:Q9Y5B8
Molecular Weight:38,187 Da
NCBI Full Name:Nucleoside diphosphate kinase 7
NCBI Synonym Full Names:NME/NM23 family member 7
NCBI Official Symbol:NME7  
NCBI Official Synonym Symbols:NDK7; NDK 7; CFAP67; MN23H7; nm23-H7  
NCBI Protein Information:nucleoside diphosphate kinase 7
UniProt Protein Name:Nucleoside diphosphate kinase 7
UniProt Synonym Protein Names:nm23-H7
Protein Family:Nucleoside diphosphate kinase
UniProt Gene Name:NME7  
UniProt Entry Name:NDK7_HUMAN
Anti-NME7 Antibody (CAB14882)Western blot analysis of extracts of various cell lines, using NME7 antibody (CAB14882) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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