Cell Biology Antibodies 9
Anti-NLGN4Y Antibody (CAB4513)
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- SKU:
- CAB4513
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- NLGN4Y
- Synonyms:
- neuroligin-4
- Synonyms:
- Y-linked
- Research Area:
- Cell Biology
Description
| Product Name: | NLGN4Y Rabbit pAb |
| Product Code: | CAB4513 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | NLGN4Y, neuroligin-4, Y-linked |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 122-256 of human NLGN4Y (NP_001157710.1). |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-87MG, U-251MG, HeLa, A-549, Mouse brain, Mouse testis, Rat brain, Rat testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 122-256 of human NLGN4Y (NP_001157710.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | DMLP IWFT TSLD TLMT YVQD QNED CLYL NIYV PMED GTNI KRNA DDIT SNDH GEDK DIHE QNSK KPVM VYIH GGSY MEGT GNMI DGSI LASY GNVI VITI NYRL GILG MQEA RLCG SSKM FNYF KSPF TNLI NFF |
| Gene ID: | 22829 |
| Uniprot: | Q8NFZ3 |
| Cellular Location: | Cell junction, Cell membrane, Single-pass type I membrane protein, postsynaptic cell membrane, postsynaptic density, synapse |
| Calculated MW: | 15kDa/28kDa/72kDa/92kDa |
| Observed MW: | 100kDa |
| UniProt Protein Function: | NLGN4Y: Putative neuronal cell surface protein involved in cell- cell-interactions. Belongs to the type-B carboxylesterase/lipase family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: Yq11.221 Cellular Component: postsynaptic membrane; extracellular space; cell surface; integral to plasma membrane; postsynaptic density; synapse; cell junction Molecular Function:protein binding; neurexin binding; receptor activity; cell adhesion molecule binding Biological Process: regulation of synaptic transmission; synaptogenesis; metabolic process; neuron adhesion; social behavior; learning |
| NCBI Summary: | This gene encodes a type I membrane protein that belongs to the family of neuroligins, which are cell adhesion molecules present at the postsynaptic side of the synapse, and may be essential for the formation of functional synapses. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Mar 2011] |
| UniProt Code: | Q8NFZ3 |
| NCBI GenInfo Identifier: | 31076823 |
| NCBI Gene ID: | 22829 |
| NCBI Accession: | Q8NFZ3.1 |
| UniProt Secondary Accession: | Q8NFZ3,Q14D08, Q7Z3T5, Q8N5B6, Q9Y2F8, F5H6W0, |
| UniProt Related Accession: | Q8NFZ3 |
| Molecular Weight: | 816 |
| NCBI Full Name: | Neuroligin-4, Y-linked |
| NCBI Synonym Full Names: | neuroligin 4, Y-linked |
| NCBI Official Symbol: | NLGN4Y |
| NCBI Protein Information: | neuroligin-4, Y-linked |
| UniProt Protein Name: | Neuroligin-4, Y-linked |
| Protein Family: | Neuroligin |
| UniProt Gene Name: | NLGN4Y |
| UniProt Entry Name: | NLGNY_HUMAN |
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