Description
system_update_altDatasheet
Product Code: | HDLA050 |
Size: | 100 µg |
Clonality: | Monoclonal |
Clone: | DM88 |
Synonyms: | NCR3,CD337,NKp30,1C7,LY117,MALS |
Applications: | ELISA, Flow Cyt |
Recommended Dilution: | ELISA 1:5000-10000; Flow Cyt 1:100 |
Host Species: | Rabbit |
Isotype: | Rabbit IgG |
Reactivity: | Human |
Purification Method: | Purified from cell culture supernatant by affinity chromatography |
Formulation: | Powder |
Buffer: | 1XPBS |
Storage: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature. |
Usage: | Research use only |
Background: | The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene. |