Cell Biology Antibodies 15
Anti-NKD1 Antibody (CAB17799)
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- SKU:
- CAB17799
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-NKD1 Antibody |
| Antibody SKU: | CAB17799 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide of Human NKD1. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | 293T, LO2 |
| Immunogen: | A synthetic peptide of Human NKD1. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 85407 |
| Uniprot: | Q969G9 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 60kDa |
 | Western blot - NKD1 Polyclonal Antibody (CAB17799) |
| Synonyms: | Naked1, NKD1 |
| Background: | In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.[supplied by OMIM, Jun 2003] |
| UniProt Protein Function: | NKD1: Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity. Interacts with DVL1, DVL2, DVL3 and PPP2R3A. Expression is induced by activation of the Wnt signaling pathway. Expressed in colon, heart, kidney, leukocyte, liver, lung, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine and spleen. Belongs to the NKD family. |
| UniProt Protein Details: | Protein type:Cell development/differentiation Chromosomal Location of Human Ortholog: 16q12.1 Cellular Component: cytoplasm; protein phosphatase type 2A complex Molecular Function:protein binding Biological Process: eye photoreceptor cell differentiation; positive regulation of protein catabolic process; somatic muscle development |
| NCBI Summary: | In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.[supplied by OMIM, Jun 2003] |
| UniProt Code: | Q969G9 |
| NCBI GenInfo Identifier: | 74731040 |
| NCBI Gene ID: | 85407 |
| NCBI Accession: | Q969G9.1 |
| UniProt Secondary Accession: | Q969G9,Q8WZ08, B2RC39, |
| UniProt Related Accession: | Q969G9 |
| Molecular Weight: | 52,285 Da |
| NCBI Full Name: | Protein naked cuticle homolog 1 |
| NCBI Synonym Full Names: | naked cuticle homolog 1 |
| NCBI Official Symbol: | NKD1 |
| NCBI Official Synonym Symbols: | Naked1 |
| NCBI Protein Information: | protein naked cuticle homolog 1 |
| UniProt Protein Name: | Protein naked cuticle homolog 1 |
| Protein Family: | Protein naked cuticle |
| UniProt Gene Name: | NKD1 |
| UniProt Entry Name: | NKD1_HUMAN |
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