Cell Biology Antibodies 7

Anti-NINJ1 Antibody (CAB16406)

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SKU:
CAB16406
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-NINJ1 Antibody
Antibody SKU:CAB16406
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NINJ1 (NP_004139.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse kidney, Rat soleen
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NINJ1 (NP_004139.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MDSG TEEY ELNG GLPP GTPG SPDA SPAR WGWR HGPI NVNH YASK KSAA ESML DIAL LMAN ASQL KAVV EQGP SFAF YVPL VVLI SISL VLQI GVGV LLIF
Gene ID:4814
Uniprot:Q92982
Cellular Location:Membrane, Multi-pass membrane protein
Calculated MW:16kDa
Observed MW:16kDa
Synonyms:NINJ1, NIN1, NINJURIN
Background:The ninjurin protein is upregulated after nerve injury both in dorsal root ganglion neurons and in Schwann cells. It demonstrates properties of a homophilic adhesion molecule and promotes neurite outgrowth from primary cultured dorsal root ganglion neurons.
UniProt Protein Function:NINJ1: Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues. Cell adhesion requires divalent cations. Belongs to the ninjurin family.
UniProt Protein Details:

Protein type:Membrane protein, integral; Cell development/differentiation; Cell adhesion; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 9q22

Cellular Component: integral to membrane

Biological Process: nervous system development; tissue regeneration; cell adhesion; positive regulation of cell-matrix adhesion

NCBI Summary:The ninjurin protein is upregulated after nerve injury both in dorsal root ganglion neurons and in Schwann cells (Araki and Milbrandt, 1996 [PubMed 8780658]). It demonstrates properties of a homophilic adhesion molecule and promotes neurite outgrowth from primary cultured dorsal root ganglion neurons.[supplied by OMIM, Aug 2009]
UniProt Code:Q92982
NCBI GenInfo Identifier:148922911
NCBI Gene ID:4814
NCBI Accession:NP_004139
UniProt Secondary Accession:Q92982,Q6GU89, Q8WUV5, Q9BT07,
UniProt Related Accession:Q92982
Molecular Weight:Predicted: 17 kDaObserved: 16 kDa
NCBI Full Name:ninjurin-1
NCBI Synonym Full Names:ninjurin 1
NCBI Official Symbol:NINJ1  
NCBI Official Synonym Symbols:NIN1; NINJURIN  
NCBI Protein Information:ninjurin-1; nerve injury-induced protein 1; nerve injury-induced protein-1
UniProt Protein Name:Ninjurin-1
UniProt Synonym Protein Names:Nerve injury-induced protein 1
Protein Family:Ninjurin
UniProt Gene Name:NINJ1  
UniProt Entry Name:NINJ1_HUMAN
Anti-NINJ1 Antibody (CAB16406)Western blot analysis of extracts of various cell lines, using NINJ1 antibody (CAB16406) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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