Neuroscience
Anti-NIF3L1 Antibody (CAB15879)
- SKU:
- CAB15879
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Neuroscience
Description
| Antibody Name: | Anti-NIF3L1 Antibody |
| Antibody SKU: | CAB15879 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-377 of human NIF3L1 (NP_001129511.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HepG2, Mouse heart |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-377 of human NIF3L1 (NP_001129511.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MLSS CVRP VPTT VRFV DSLI CNSS RSFM DLKA LLSS LNDF ASLS FAES WDNV GLLV EPSP PHTV NTLF LTND LTEE VMEE VLQK KADL ILSY HPPI FRPM KRIT WNTW KERL VIRA LENR VGIY SPHT AYDA APQG VNNW LAKG LGAC TSRP IHPS KAPN YPTE GNHR VEFN VNYT QDLD KVMS AVKG IDGV SVTS FSAR TGNE EQTR INLN CTQK ALMQ VVDF LSRN KQLY QKTE ILSL EKPL LLHT GMGR LCTL DESV SLAT MIDR IKRH LKLS HIRL ALGV GRTL ESQV KVVA LCAG SGSS VLQG VEAD LYLT GEMS HHDT LDAA SQGI NVIL CEHS NTER GFLS DLRD MLDS HLEN KINI ILSE TDRD PLQV V |
| Gene ID: | 60491 |
| Uniprot: | Q9GZT8 |
| Cellular Location: | Cytoplasm, Nucleus |
| Calculated MW: | 32kDa/38kDa/41kDa |
| Observed MW: | 42kDa |
| Synonyms: | NIF3L1, ALS2CR1, CALS-7, MDS015 |
| Background: |
| UniProt Protein Function: | NIF3L1: Belongs to the UPF0135 (NIF3) family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 3.5.4.16; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 2q33 Cellular Component: mitochondrion; cytoplasm Molecular Function:GTP cyclohydrolase I activity; protein binding; GTP binding; metal ion binding; transcription factor binding Biological Process: positive regulation of transcription, DNA-dependent |
| UniProt Code: | Q9GZT8 |
| NCBI GenInfo Identifier: | 56605983 |
| NCBI Gene ID: | 60491 |
| NCBI Accession: | NP_068596 |
| UniProt Secondary Accession: | Q9GZT8,Q53TX4, Q6X735, Q9H2D2, Q9HC18, |
| UniProt Related Accession: | Q9GZT8 |
| Molecular Weight: | 32,164 Da |
| NCBI Full Name: | NIF3-like protein 1 isoform 2 |
| NCBI Synonym Full Names: | NIF3 NGG1 interacting factor 3-like 1 |
| NCBI Official Symbol: | NIF3L1 |
| NCBI Official Synonym Symbols: | CALS-7; MDS015; ALS2CR1 |
| NCBI Protein Information: | NIF3-like protein 1 |
| UniProt Protein Name: | NIF3-like protein 1 |
| UniProt Synonym Protein Names: | Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein |
| UniProt Gene Name: | NIF3L1 |
| UniProt Entry Name: | GTPC1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using NIF3L1 antibody (CAB15879) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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