Cell Biology Antibodies 5
Anti-NHS Antibody (CAB15295)
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- SKU:
- CAB15295
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-NHS Antibody |
| Antibody SKU: | CAB15295 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 600-900 of human NHS (NP_938011.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:200 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | 293T, Raji |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 600-900 of human NHS (NP_938011.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MDQK DDHQ SSSG NWSG SSST CPSQ TSET IPPA ASPP LTGS SHCD SELS LNTA PHAN EDAS VFVT EQYN DHLD KVRG HRAN SFTS TVAD LLDD PNNS NTSD SEWN YLHH HHDA SCRQ DFSP ERPK ADSL GCPS FTSM ATYD SFLE KSPS DKAD TSSH FSVD TEGY YTSM HFDC GLKG NKSY VCHY AALG PENG QGVG ASPG LPDC AWQD YLDH KRQG RPSI SFRK PKAK PTPP KRSS SLRK SDGN ADIS EKKE PKIS SGQH LPHS SREM KLPL DFAN TPSR MENA NLPT KQEP SWIN QSEQ G |
| Gene ID: | 4810 |
| Uniprot: | Q6T4R5 |
| Cellular Location: | Apical cell membrane, Cell junction, Cell projection, Cytoplasm, Peripheral membrane protein, focal adhesion, lamellipodium, tight junction |
| Calculated MW: | 160kDa/176kDa/179kDa |
| Observed MW: | 179kDa |
| Synonyms: | NHS, CTRCT40, CXN, SCML1 |
| Background: | This gene encodes a protein containing four conserved nuclear localization signals. The encoded protein functions in eye, tooth, craniofacial and brain development, and it can regulate actin remodeling and cell morphology. Mutations in this gene have been shown to cause Nance-Horan syndrome, and also X-linked cataract-40. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| UniProt Code: | Q6T4R5 |
| NCBI GenInfo Identifier: | 38093637 |
| NCBI Gene ID: | |
| NCBI Accession: | NP_938011.1 |
| Molecular Weight: | |
| NCBI Full Name: | Nance-Horan syndrome protein isoform 1 |
| UniProt Protein Name: | Nance-Horan syndrome protein |
| UniProt Synonym Protein Names: | Congenital cataracts and dental anomalies protein |
| Protein Family: | NHS-like protein |
| UniProt Gene Name: | NHS |
| UniProt Entry Name: | NHS_HUMAN |
 | Western blot analysis of extracts of various cell lines, using NHS antibody (CAB15295) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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