Epigenetics & Nuclear Signaling Antibodies 4

Anti-NFYC Antibody (CAB9832)

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SKU:
CAB9832
Product Type:
Antibody
Applications:
WB
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-NFYC Antibody
Antibody SKU:CAB9832
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 86-335 of human NFYC (NP_055038.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse kidney, Mouse heart
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 86-335 of human NFYC (NP_055038.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:IHTE DNKR RTLQ RNDI AMAI TKFD QFDF LIDI VPRD ELKP PKRQ EEVR QSVT PAEP VQYY FTLA QQPT AVQV QGQQ QGQQ TTSS TTTI QPGQ IIIA QPQQ GQTT PVTM QVGE GQQV QIVQ AQPQ GQAQ QAQS GTGQ TMQV MQQI ITNT GEIQ QIPV QLNA GQLQ YIRL AQPV SGTQ VVQG QIQT LATN AQQI TQTE VQQG QQQF SQFT DGQQ LYQI QQVT MPAG QDLA QPMF IQSA NQPS DGQA PQVT GD
Gene ID:4802
Uniprot:Q13952
Cellular Location:Nucleus
Calculated MW:32kDa/33kDa/37kDa/39kDa/48kDa/50kDa
Observed MW:50kDa
Synonyms:NFYC, CBF-C, CBFC, H1TF2A, HAP5, HSM, NF-YC
Background:This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.
NCBI Summary:This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
UniProt Code:Q13952
NCBI GenInfo Identifier:20137773
NCBI Gene ID:4802
NCBI Accession:Q13952.3
UniProt Secondary Accession:Q13952,Q59GY4, Q5T6K8, Q5T6K9, Q5T6L1, Q5TZR6, Q92869 Q9HBX1, B4DUS6, B4DW63, D3DPV9, F8VWM3,
UniProt Related Accession:Q13952
Molecular Weight:37,066 Da
NCBI Full Name:Nuclear transcription factor Y subunit gamma
NCBI Synonym Full Names:nuclear transcription factor Y subunit gamma
NCBI Official Symbol:NFYC  
NCBI Official Synonym Symbols:HSM; CBFC; HAP5; CBF-C; NF-YC; H1TF2A  
NCBI Protein Information:nuclear transcription factor Y subunit gamma
UniProt Protein Name:Nuclear transcription factor Y subunit gamma
UniProt Synonym Protein Names:CAAT box DNA-binding protein subunit C; Nuclear transcription factor Y subunit C; NF-YC; Transactivator HSM-1/2
Protein Family:Nuclear transcription factor
UniProt Gene Name:NFYC  
UniProt Entry Name:NFYC_HUMAN
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