Epigenetics & Nuclear Signaling Antibodies 1
Anti-NFRKB Antibody (CAB10124)
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- SKU:
- CAB10124
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-NFRKB Antibody |
| Antibody SKU: | CAB10124 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human NFRKB (NP_001137307.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | HepG2, Jurkat, HeLa |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human NFRKB (NP_001137307.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MDSL DHML TDPL ELGP CGDG HGTR IMED CLLG GTRV SLPE DLLE DPEI FFDV VSLS TWQE VLSD SQRE HLQQ FLPQ FPED SAEQ QNEL ILAL FSGE NFRF GNPL HIAQ KLFR DGHF NPEV VKYR QLCF KSQY KRYL NSQQ QYFH RLLK QILA SRSD LLEM ARRS GPAL PFRQ KRPS PSRT PEER EWRT QQRY LKVL REVK EECG DTAL SSDE EDLS SWLP SSPA RSPS PAVP LRVV PTLS TTDM KTAD KVEL GDSD LKIM LKKH HEKR KHQP DHPD LLTG DLTL NDIM TRVN AGRK GSLA ALYD LAVL KKKV KEKE EKKK KKIK TIKS EAED LAEP LSST |
| Gene ID: | 4798 |
| Uniprot: | Q6P4R8 |
| Cellular Location: | Nucleus |
| Calculated MW: | 138kDa/139kDa/141kDa |
| Observed MW: | 185kDa |
| Synonyms: | NFRKB, INO80G |
| Background: |
| UniProt Protein Function: | NFRKB: Binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'. Belongs to the NFRKB family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transcription factor Chromosomal Location of Human Ortholog: 11q24-q25 Cellular Component: nucleoplasm; nucleus Molecular Function:protein binding; protease binding; DNA binding Biological Process: transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; DNA repair; inflammatory response; DNA recombination |
| UniProt Code: | Q6P4R8 |
| NCBI GenInfo Identifier: | 23346420 |
| NCBI Gene ID: | 4798 |
| NCBI Accession: | NP_006156.2 |
| UniProt Secondary Accession: | Q6P4R8,Q12869, Q15312, Q9H048, |
| UniProt Related Accession: | Q6P4R8 |
| Molecular Weight: | 139,001 Da |
| NCBI Full Name: | nuclear factor related to kappa-B-binding protein isoform 2 |
| NCBI Synonym Full Names: | nuclear factor related to kappaB binding protein |
| NCBI Official Symbol: | NFRKB |
| NCBI Official Synonym Symbols: | INO80G |
| NCBI Protein Information: | nuclear factor related to kappa-B-binding protein; INO80 complex subunit G; DNA-binding protein R kappa B; DNA-binding protein R kappa-B |
| UniProt Protein Name: | Nuclear factor related to kappa-B-binding protein |
| UniProt Synonym Protein Names: | DNA-binding protein R kappa-B; INO80 complex subunit G |
| Protein Family: | Bacteriophage adsorption protein |
| UniProt Gene Name: | NFRKB |
| UniProt Entry Name: | NFRKB_HUMAN |
 | Western blot analysis of extracts of various cell lines, using NFRKB antibody (CAB10124) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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