Anti-NFIB / NF1B2 Antibody (CAB9125)
- SKU:
- CAB9125
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CTF
- Synonyms:
- HMGIC/NFIB
- Synonyms:
- NF-I/B
- Synonyms:
- NF1-B
- Synonyms:
- NFI-B
- Synonyms:
- NFI-RED
- Synonyms:
- NFIB2
- Synonyms:
- NFIB3
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Product Name: | NFIB / NF1B2 Rabbit mAb |
| Product Code: | CAB9125 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | CTF, HMGIC/NFIB, NF-I/B, NF1-B, NFI-B, NFI-RED, NFIB2, NFIB3 |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human NFIB / NF1B2 |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | SH-SY5Y, Mouse lung |
| Immunogen: | A synthesized peptide derived from human NFIB / NF1B2 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 4781 |
| Uniprot: | O00712 |
| Calculated MW: | 47kDa |
| Observed MW: | 47KDa |
| UniProt Protein Function: | NFI-B: Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. Belongs to the CTF/NF-I family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 9p24.1 Cellular Component: nucleoplasm; nucleolus; nucleus Molecular Function:DNA binding; double-stranded DNA binding Biological Process: transcription from RNA polymerase II promoter; pontine nucleus development; glial cell differentiation; anterior commissure morphogenesis; chondrocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; DNA replication; negative regulation of DNA binding; hindbrain development |
| UniProt Code: | O00712 |
| NCBI GenInfo Identifier: | 45644934 |
| NCBI Gene ID: | 4781 |
| NCBI Accession: | O00712.2 |
| UniProt Secondary Accession: | O00712,O00166, Q12858, Q5VW29, Q63HM5, Q6ZNF9, Q96J45 G3V1P1, H7BYE8, |
| UniProt Related Accession: | O00712 |
| Molecular Weight: | 420 |
| NCBI Full Name: | Nuclear factor 1 B-type |
| NCBI Synonym Full Names: | nuclear factor I/B |
| NCBI Official Symbol: | NFIB |
| NCBI Official Synonym Symbols: | CTF; NF1-B; NFI-B; NFIB2; NFIB3; NF-I/B; NFI-RED; HMGIC/NFIB |
| NCBI Protein Information: | nuclear factor 1 B-type; nuclear factor 1/B; TGGCA-binding protein; CCAAT-box-binding transcription factor |
| UniProt Protein Name: | Nuclear factor 1 B-type |
| UniProt Synonym Protein Names: | CCAAT-box-binding transcription factor; CTF; Nuclear factor I/B; NF-I/B; NFI-B; TGGCA-binding protein |
| Protein Family: | Nuclear factor |
| UniProt Gene Name: | NFIB |
| UniProt Entry Name: | NFIB_HUMAN |
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