Cell Biology Antibodies 12
Anti-Neurotrimin Antibody (CAB8994)
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- SKU:
- CAB8994
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-Neurotrimin Antibody |
| Antibody SKU: | CAB8994 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-316 of human NTM (NP_001137531.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:200 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HT-1080, SW480, Mouse eye, Mouse liver, Rat eye |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-316 of human NTM (NP_001137531.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | PVRS GDAT FPKA MDNV TVRQ GESA TLRC TIDN RVTR VAWL NRST ILYA GNDK WCLD PRVV LLSN TQTQ YSIE IQNV DVYD EGPY TCSV QTDN HPKT SRVH LIVQ VSPK IVEI SSDI SINE GNNI SLTC IATG RPEP TVTW RHIS PKAV GFVS EDEY LEIQ GITR EQSG DYEC SASN DVAA PVVR RVKV TVNY PPYI SEAK GTGV PVGQ KGTL QCEA SAVP SAEF QWYK DDKR LIEG KKGV KVEN RPFL SKLI FFNV SEHD YGNY TCVA SNKL GHTN ASIM LFGE TVL |
| Gene ID: | 50863 |
| Uniprot: | Q9P121 |
| Cellular Location: | Cell membrane, GPI-anchor, Lipid-anchor |
| Calculated MW: | 34kDa/37kDa/39kDa |
| Observed MW: | 38kDa |
| Synonyms: | NTM, HNT, IGLON2, NTRI |
| Background: | This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules. The encoded protein may promote neurite outgrowth and adhesion via a homophilic mechanism. This gene is closely linked to a related family member, opioid binding protein/cell adhesion molecule-like (OPCML), on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | NT: Neural cell adhesion molecule. Belongs to the immunoglobulin superfamily. IgLON family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell adhesion; Membrane protein, GPI anchor Chromosomal Location of Human Ortholog: 11q25 Cellular Component: neuron projection; cell surface; cell soma; plasma membrane; intercellular junction Molecular Function:protein binding Biological Process: cell-cell adhesion; regulation of neurogenesis; neuron recognition; cell adhesion |
| NCBI Summary: | This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules. The encoded protein may promote neurite outgrowth and adhesion via a homophilic mechanism. This gene is closely linked to a related family member, opioid binding protein/cell adhesion molecule-like (OPCML), on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009] |
| UniProt Code: | Q9P121 |
| NCBI GenInfo Identifier: | 7705413 |
| NCBI Gene ID: | 50863 |
| NCBI Accession: | |
| UniProt Related Accession: | Q9P121 |
| Molecular Weight: | |
| NCBI Full Name: | neurotrimin isoform 1 |
| NCBI Synonym Full Names: | neurotrimin |
| NCBI Official Symbol: | NTM |
| NCBI Official Synonym Symbols: | HNT; NTRI; CEPU-1; IGLON2 |
| NCBI Protein Information: | neurotrimin |
| UniProt Protein Name: | Neurotrimin |
| UniProt Synonym Protein Names: | IgLON family member 2 |
| Protein Family: | Neurotrimin |
| UniProt Gene Name: | NTM |
| UniProt Entry Name: | NTRI_HUMAN |
 | Western blot analysis of extracts of various cell lines, using NTM antibody (CAB8994) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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