Anti-Nectin4 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0276)
- SKU:
- HDAB0276
- Product Type:
- Rabbit Monoclonal Antibody
- Antibody Type:
- Monoclonal Antibody
- Size:
- 100 μg
- Reactivity:
- Human
- Host Species:
- Rabbit
- Antibody Isotype:
- Rabbit/Human Fc chimeric IgG1
- Clone:
- DMC438
- Synonyms:
- EDSS1, LNIR, nectin-4, PRR4, PVRL4
Description
system_update_altDatasheet
| SKU: | HDAB0276 |
| Size: | 100 µg |
| Clonality: | Monoclonal |
| Clone: | DMC438 |
| Synonyms: | EDSS1, LNIR, nectin-4, PRR4, PVRL4 |
| Applications: | Flow Cyt |
| Recommended Dilution: | Flow Cyt 1:100 |
| Host Species: | Rabbit |
| Isotype: | Rabbit/Human Fc chimeric IgG1 |
| Reactivity: | Human |
| Purification Method: | Purified from cell culture supernatant by affinity chromatography |
| Formulation: | Powder |
| Buffer: | 1XPBS |
| Storage: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature. |
| Usage: | Research use only |
| Background: | This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined. |