Cell Biology Antibodies 9
Anti-NDUFV3 Antibody (CAB3986)
- SKU:
- CAB3986
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-NDUFV3 Antibody |
Antibody SKU: | CAB3986 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-108 of human NDUFV3 (NP_001001503.1). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human |
Positive Samples: | HepG2 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-108 of human NDUFV3 (NP_001001503.1). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MAAP CLLR QGRA GALK TMLQ EAQV FRGL ASTV SLSA ESGK SEKG QPQN SKKQ SPPK KPAP VPAE PFDN TTYK NLQH HDYS TYTF LDLN LELS KFRM PQPS SGRE SPRH |
Gene ID: | 4731 |
Uniprot: | P56181 |
Cellular Location: | Matrix side, Mitochondrion inner membrane, Peripheral membrane protein |
Calculated MW: | 11kDa/50kDa |
Observed MW: | 10kDa |
Synonyms: | NDUFV3, CI-10k, CI-9KD |
Background: | The protein encoded by this gene is one of at least forty-one subunits that make up the NADH-ubiquinone oxidoreductase complex. This complex is part of the mitochondrial respiratory chain and serves to catalyze the rotenone-sensitive oxidation of NADH and the reduction of ubiquinone. The encoded protein is one of three proteins found in the flavoprotein fraction of the complex. The specific function of the encoded protein is unknown. Two transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | NDUFV3: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFV3 subunit family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Mitochondrial; Oxidoreductase; Energy Metabolism - oxidative phosphorylation Chromosomal Location of Human Ortholog: 21q22.3 Cellular Component: mitochondrial inner membrane; mitochondrial respiratory chain complex I; mitochondrion; nucleoplasm Biological Process: mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly |
NCBI Summary: | The protein encoded by this gene is one of at least forty-one subunits that make up the NADH-ubiquinone oxidoreductase complex. This complex is part of the mitochondrial respiratory chain and serves to catalyze the rotenone-sensitive oxidation of NADH and the reduction of ubiquinone. The encoded protein is one of three proteins found in the flavoprotein fraction of the complex. The specific function of the encoded protein is unknown. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | P56181 |
NCBI GenInfo Identifier: | 20178326 |
NCBI Gene ID: | 4731 |
NCBI Accession: | P56181.2 |
UniProt Secondary Accession: | P56181,Q6FGD3, Q8WU60, Q9HCR5, A8K0M1, J3KNX7, |
UniProt Related Accession: | P56181 |
Molecular Weight: | 50,984 Da |
NCBI Full Name: | NADH dehydrogenase |
NCBI Synonym Full Names: | NADH:ubiquinone oxidoreductase subunit V3 |
NCBI Official Symbol: | NDUFV3 |
NCBI Official Synonym Symbols: | CI-10k; CI-9KD |
NCBI Protein Information: | NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial |
UniProt Protein Name: | NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial |
UniProt Synonym Protein Names: | Complex I-9kD; CI-9kD; NADH-ubiquinone oxidoreductase 9 kDa subunit; Renal carcinoma antigen NY-REN-4 |
Protein Family: | NADH dehydrogenase [ubiquinone] flavoprotein |
UniProt Gene Name: | NDUFV3 |
UniProt Entry Name: | NDUV3_HUMAN |
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