Cell Biology Antibodies 8

Anti-NCR2 Antibody (CAB3657)

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SKU:
CAB3657
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-NCR2 Antibody
Antibody SKU:CAB3657
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 22-192 of human NCR2 (NP_004819.2).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Human
Positive Samples:Raji
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 22-192 of human NCR2 (NP_004819.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:QSKA QVLQ SVAG QTLT VRCQ YPPT GSLY EKKG WCKE ASAL VCIR LVTS SKPR TMAW TSRF TIWD DPDA GFFT VTMT DLRE EDSG HYWC RIYR PSDN SVSK SVRF YLVV SPAS ASTQ TSWT PRDL VSSQ TQTQ SCVP PTAG ARQA PESP STIP VPSQ PQNS TLRP GPAA PIA
Gene ID:9436
Uniprot:O95944
Cellular Location:Cell membrane, Single-pass type I membrane protein
Calculated MW:28kDa/29kDa/30kDa
Observed MW:44kDa
Synonyms:NCR2, CD336, LY95, NK-p44, NKP44, dJ149M18.1
Background:
UniProt Protein Function:NCR2: Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Belongs to the natural cytotoxicity receptor (NCR) family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, integral

Chromosomal Location of Human Ortholog: 6p21.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function:transmembrane receptor activity

Biological Process: innate immune response; cellular defense response; signal transduction

UniProt Code:O95944
NCBI GenInfo Identifier:251757303
NCBI Gene ID:9436
NCBI Accession:O95944.2
UniProt Secondary Accession:O95944,Q9H562, Q9H563, Q9H564, Q9UMT1, Q9UMT2,
UniProt Related Accession:O95944
Molecular Weight:276
NCBI Full Name:Natural cytotoxicity triggering receptor 2
NCBI Synonym Full Names:natural cytotoxicity triggering receptor 2
NCBI Official Symbol:NCR2  
NCBI Official Synonym Symbols:LY95; CD336; NKP44; NK-p44; dJ149M18.1  
NCBI Protein Information:natural cytotoxicity triggering receptor 2; NK cell-activating receptor; NK cell activating receptor (NKp44); natural killer cell p44-related protein; lymphocyte antigen 95 (activating NK-receptor; NK-p44); lymphocyte antigen 95 homolog (activating NK-rec
UniProt Protein Name:Natural cytotoxicity triggering receptor 2
UniProt Synonym Protein Names:Lymphocyte antigen 95 homolog; NK cell-activating receptor; Natural killer cell p44-related protein; NK-p44; NKp44; CD_antigen: CD336
Protein Family:Natural cytotoxicity triggering receptor
UniProt Gene Name:NCR2  
UniProt Entry Name:NCTR2_HUMAN
Anti-NCR2 Antibody (CAB3657)Western blot analysis of extracts of Raji cells, using NCR2 antibody (CAB3657) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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