Cell Biology Antibodies 8
Anti-NCAN Antibody (CAB3052)
- SKU:
- CAB3052
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-NCAN Antibody |
| Antibody SKU: | CAB3052 |
| Antibody Size: | 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide of human NCAN |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:25 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: |
| Immunogen: | A synthetic peptide of human NCAN |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 1463 |
| Uniprot: | O14594 |
| Cellular Location: | Secreted |
| Calculated MW: | 143kDa |
| Observed MW: | Refer to figures |
| Synonyms: | NCAN, CSPG3, neurocan |
| Background: |
| UniProt Protein Function: | CSPG3: May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM). Chondroitin sulfate proteoglycan; binds to hyaluronic acid. Belongs to the aggrecan/versican proteoglycan family. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted; Cell adhesion Chromosomal Location of Human Ortholog: 19p12 Cellular Component: proteinaceous extracellular matrix; lysosomal lumen; Golgi lumen; extracellular region Molecular Function:extracellular matrix structural constituent; hyaluronic acid binding; calcium ion binding; carbohydrate binding Biological Process: axon guidance; extracellular matrix organization and biogenesis; central nervous system development; chondroitin sulfate biosynthetic process; glycosaminoglycan metabolic process; pathogenesis; dermatan sulfate biosynthetic process; chondroitin sulfate metabolic process; chondroitin sulfate catabolic process; carbohydrate metabolic process; regulation of synapse structural plasticity; cell adhesion; skeletal development |
| NCBI Summary: | Neurocan is a chondroitin sulfate proteoglycan thought to be involved in the modulation of cell adhesion and migration.[supplied by OMIM, Jul 2002] |
| UniProt Code: | O14594 |
| NCBI GenInfo Identifier: | 160332364 |
| NCBI Gene ID: | 1463 |
| NCBI Accession: | O14594.3 |
| UniProt Secondary Accession: | O14594,Q9UPK6, |
| UniProt Related Accession: | O14594 |
| Molecular Weight: | 1321 |
| NCBI Full Name: | Neurocan core protein |
| NCBI Synonym Full Names: | neurocan |
| NCBI Official Symbol: | NCAN |
| NCBI Official Synonym Symbols: | CSPG3 |
| NCBI Protein Information: | neurocan core protein; neurocan proteoglycan; chondroitin sulfate proteoglycan 3 (neurocan) |
| UniProt Protein Name: | Neurocan core protein |
| UniProt Synonym Protein Names: | Chondroitin sulfate proteoglycan 3 |
| Protein Family: | Neurocan core protein |
| UniProt Gene Name: | NCAN |
| UniProt Entry Name: | NCAN_HUMAN |
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