Anti-NAT10 Antibody (CAB19286)
- SKU:
- CAB19286
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- NAT10
- Synonyms:
- ALP
- Synonyms:
- NET43
- Synonyms:
- Kre33
- Synonyms:
- N-acetyltransferase 10
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Product Name: | NAT10 Rabbit mAb |
| Product Code: | CAB19286 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | NAT10, ALP, NET43, Kre33, N-acetyltransferase 10 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human NAT10. |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, K-562, SH-SY5Y, Mouse testis |
| Immunogen: | Recombinant protein of human NAT10. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 55226 |
| Uniprot: | Q9H0A0 |
| Cellular Location: | Nucleus, nucleolus |
| Calculated MW: | 116kDa |
| Observed MW: | 120KDa |
| UniProt Protein Function: | ALP: Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division. Belongs to the UPF0202 family. |
| UniProt Protein Details: | Protein type:EC 2.3.1.-; Acetyltransferase; Nucleolus Chromosomal Location of Human Ortholog: 11p13 Cellular Component: membrane; nucleolus; nucleus Molecular Function:N-acetyltransferase activity; ATP binding Biological Process: metabolic process |
| NCBI Summary: | The protein encoded by this gene is an RNA cytidine acetyltransferase involved in histone acetylation, tRNA acetylation, the biosynthesis of 18S rRNA, and the enhancement of nuclear architecture and chromatin organization. [provided by RefSeq, Oct 2016] |
| UniProt Code: | Q9H0A0 |
| NCBI GenInfo Identifier: | 313104140 |
| NCBI Gene ID: | 55226 |
| NCBI Accession: | Q9H0A0.2 |
| UniProt Related Accession: | Q9H0A0 |
| Molecular Weight: | |
| NCBI Full Name: | RNA cytidine acetyltransferase |
| NCBI Synonym Full Names: | N-acetyltransferase 10 |
| NCBI Official Symbol: | NAT10 |
| NCBI Official Synonym Symbols: | ALP; Kre33; NET43 |
| NCBI Protein Information: | RNA cytidine acetyltransferase |
| UniProt Protein Name: | N-acetyltransferase 10 |
| Protein Family: | Putative nucleobase-ascorbate transporter |
| UniProt Gene Name: | NAT10 |
| UniProt Entry Name: | NAT10_HUMAN |
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