Cell Biology Antibodies 15
Anti-NAF1 Antibody (CAB17809)
- SKU:
- CAB17809
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-NAF1 Antibody |
Antibody SKU: | CAB17809 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 150-400 of human NAF1 (NP_612395.2). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | K-562, Mouse testis |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 150-400 of human NAF1 (NP_612395.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | PPVL SDGD DDLQ IEKE NKNF PLKT KDEL LLNE LPSV EELT IILP EDIE LKPL GMVS SIIE QLVI IESM TNLP PVNE ETVI FKSD RQAA GKIF EIFG PVAH PFYV LRFN SSDH IESK GIKI KETM YFAP SMKD FTQY IFTE KLKQ DKGS DASW KNDQ EPPP EALD FSDD EKEK EAKQ RKKS QIQG RKKL KSEF NEPG EDFT EVHQ NWNA HSSA SEHA KGYR NREF TRGF SRAR YPRS CHGR PPPQ HFYN SEH |
Gene ID: | 92345 |
Uniprot: | Q96HR8 |
Cellular Location: | |
Calculated MW: | |
Observed MW: | 62-70kDa |
Synonyms: | NAF1 |
Background: |
UniProt Protein Function: | NAF1: RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4. Belongs to the NAF1 family. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 4q32.2 Cellular Component: small nucleolar ribonucleoprotein complex; cytoplasm; nucleus Molecular Function:protein binding; RNA binding Biological Process: pseudouridine synthesis; ribosome biogenesis and assembly; rRNA processing |
UniProt Code: | Q96HR8 |
NCBI GenInfo Identifier: | 193083172 |
NCBI Gene ID: | 92345 |
NCBI Accession: | NP_001122403.1 |
UniProt Secondary Accession: | Q96HR8,D3DP28, E9PAZ2, |
UniProt Related Accession: | Q96HR8 |
Molecular Weight: | 41,895 Da |
NCBI Full Name: | H/ACA ribonucleoprotein complex non-core subunit NAF1 isoform b |
NCBI Synonym Full Names: | nuclear assembly factor 1 ribonucleoprotein |
NCBI Official Symbol: | NAF1 |
NCBI Protein Information: | H/ACA ribonucleoprotein complex non-core subunit NAF1 |
UniProt Protein Name: | H/ACA ribonucleoprotein complex non-core subunit NAF1 |
Protein Family: | H/ACA ribonucleoprotein complex |
UniProt Gene Name: | NAF1 |
UniProt Entry Name: | NAF1_HUMAN |