Epigenetics & Nuclear Signaling Antibodies 2
Anti-NAB1 Antibody (CAB15692)
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- SKU:
- CAB15692
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-NAB1 Antibody |
| Antibody SKU: | CAB15692 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 278-487 of human NAB1 (NP_005957.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | LO2, HeLa |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 278-487 of human NAB1 (NP_005957.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | EAAA QLCV KDNA LLTR RDEL FALA RQIS REVT YKYT YRTT KSKC GERD ELSP KRIK VEDG FPDF QDSV QTLF QQAR AKSE ELAA LSSQ QPEK VMAK QMEF LCNQ AGYE RLQH AERR LSAG LYRQ SSEE HSPN GLTS DNSD GQGE RPLN LRMP NLQN RQPH HFVV DGEL SRLY PSEA KSHS SESL GILK DYPH SAFT LEKK VIKT EPED SR |
| Gene ID: | 4664 |
| Uniprot: | Q13506 |
| Cellular Location: | Nucleus |
| Calculated MW: | 51kDa/54kDa |
| Observed MW: | 54kDa |
| Synonyms: | NAB1 |
| Background: |
| UniProt Protein Function: | NAB1: Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Belongs to the NAB family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 2q32.3-q33 Cellular Component: nucleus Molecular Function:transcription factor binding Biological Process: Schwann cell differentiation; myelination; transcription, DNA-dependent; regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; regulation of epidermis development; endochondral ossification |
| UniProt Code: | Q13506 |
| NCBI GenInfo Identifier: | 56550107 |
| NCBI Gene ID: | 4664 |
| NCBI Accession: | NP_005957.2 |
| UniProt Secondary Accession: | Q13506,O75383, O75384, Q6GTU1, Q9UEV1, |
| UniProt Related Accession: | Q13506 |
| Molecular Weight: | 51,233 Da |
| NCBI Full Name: | Homo sapiens NGFI-A binding protein 1 (EGR1 binding protein 1) (NAB1), mRNA |
| NCBI Synonym Full Names: | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NCBI Official Symbol: | NAB1 |
| NCBI Protein Information: | NGFI-A-binding protein 1; EGR-1-binding protein 1; EGR1 binding protein 1; transcriptional regulatory protein p54 |
| UniProt Protein Name: | NGFI-A-binding protein 1 |
| UniProt Synonym Protein Names: | EGR-1-binding protein 1; Transcriptional regulatory protein p54 |
| Protein Family: | NGFI-A-binding protein |
| UniProt Gene Name: | NAB1 |
| UniProt Entry Name: | NAB1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using NAB1 antibody (CAB15692) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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