Epigenetics & Nuclear Signaling Antibodies 1
Anti-MZF1 Antibody (CAB10356)
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- SKU:
- CAB10356
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-MZF1 Antibody |
| Antibody SKU: | CAB10356 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-350 of human MZF1 (NP_003413.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, A-431, U-251MG, 293T, SGC-7901, Mouse brain, Mouse lung, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-350 of human MZF1 (NP_003413.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | IQAR VQGQ RPGS PEEA AALV DGLR REPG GPRR WVTV QVQG QEVL SEKM EPSS FQPL PETE PPTP EPGP KTPP RTMQ ESPL GLQV KEES EVTE DSDF LESG PLAA TQES VPTL LPEE AQRC GTVL DQIF PHSK TGPE GPSW REHP RALW HEEA GGIF SPGF ALQL GSIS AGPG SVSP HLHV PWDL GMAG LSGQ IQSP SREG GFAH ALLL PSDL RSEQ DPTD EDPC RGVG PALI TTRW RSPR GRSR GRPS TGG |
| Gene ID: | 7593 |
| Uniprot: | P28698 |
| Cellular Location: | Nucleus |
| Calculated MW: | 31kDa/54kDa/82kDa |
| Observed MW: | 110kDa |
| Synonyms: | MZF1, MZF-1, MZF1B, ZFP98, ZNF42, ZSCAN6 |
| Background: |
| UniProt Protein Function: | MZF-1: Binds to target promoter DNA and functions as trancription regulator. Regulates transcription from the PADI1 and CDH2 promoter. May be one regulator of transcriptional events during hemopoietic development. Belongs to the krueppel C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:C2H2-type zinc finger protein; DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 19q13.43 Cellular Component: nucleus Molecular Function:protein binding; protein homodimerization activity Biological Process: negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent |
| UniProt Code: | P28698 |
| NCBI GenInfo Identifier: | 215274121 |
| NCBI Gene ID: | 7593 |
| NCBI Accession: | P28698.3 |
| UniProt Secondary Accession: | P28698,Q7Z729, Q96I71, Q9NRY0, Q9UBW2, M0QXU0, |
| UniProt Related Accession: | P28698 |
| Molecular Weight: | 82kDa |
| NCBI Full Name: | Myeloid zinc finger 1 |
| NCBI Synonym Full Names: | myeloid zinc finger 1 |
| NCBI Official Symbol: | MZF1 |
| NCBI Official Synonym Symbols: | MZF-1; MZF1B; ZFP98; ZNF42; ZSCAN6 |
| NCBI Protein Information: | myeloid zinc finger 1 |
| UniProt Protein Name: | Myeloid zinc finger 1 |
| UniProt Synonym Protein Names: | Zinc finger and SCAN domain-containing protein 6; Zinc finger protein 42 |
| Protein Family: | Myeloid zinc finger |
| UniProt Gene Name: | MZF1 |
 | Western blot analysis of extracts of various cell lines, using MZF1 antibody (CAB10356) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3s. |
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