Neuroscience

Anti-MYRIP Antibody (CAB16511)

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SKU:
CAB16511
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Neuroscience

Description

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Antibody Name:Anti-MYRIP Antibody
Antibody SKU:CAB16511
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 551-770 of human MYRIP (NP_001271354.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 551-770 of human MYRIP (NP_001271354.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:VSLC NIST EVLK VINA TEEL IAGS TGPW ESPQ VPPD RQKG MFPR GTDQ VRLD EQLT SLEE NVYL AAGT VYGL ETQL TELE DAAR CIHS GTDE THLA DLED QVAT AAAQ VHHA ELQI SDIE SRIS ALTI AGLN IAPC VRFT RRRD QKQR TQVQ TIDT SRQQ RRKL PAPP VKAE KIET SSVT TIKT FNHN FILQ GSST NRTK ERKG TTKD LMEP ALES AVMY
Gene ID:25924
Uniprot:Q8NFW9
Cellular Location:Cytoplasm, Cytoplasmic vesicle, perinuclear region, secretory vesicle
Calculated MW:71kDa/74kDa/83kDa/88kDa/95kDa
Observed MW:Refer to figures
Synonyms:MYRIP, SLAC2-C, SLAC2C
Background:
UniProt Protein Function:MYRIP: Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. Functions as a protein kinase A-anchoring protein (AKAP). May act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis, including insulin release. 5 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 3p22.1

Cellular Component: perinuclear region of cytoplasm

Molecular Function:protein binding

Biological Process: positive regulation of insulin secretion

UniProt Code:Q8NFW9
NCBI GenInfo Identifier:116242669
NCBI Gene ID:25924
NCBI Accession:Q8NFW9.2
UniProt Secondary Accession:Q8NFW9,Q32M41, Q32M42, Q569F7, Q8IUF5, Q9Y3V4, B3KWM3 B3KWW4, B7Z2H1, B7Z9V3, G3XAI8,
UniProt Related Accession:Q8NFW9
Molecular Weight:83,948 Da
NCBI Full Name:Rab effector MyRIP
NCBI Synonym Full Names:myosin VIIA and Rab interacting protein
NCBI Official Symbol:MYRIP  
NCBI Official Synonym Symbols:SLAC2C; SLAC2-C  
NCBI Protein Information:rab effector MyRIP
UniProt Protein Name:Rab effector MyRIP
UniProt Synonym Protein Names:Exophilin-8; Myosin-VIIa- and Rab-interacting protein; Synaptotagmin-like protein lacking C2 domains C; SlaC2-c; Slp homolog lacking C2 domains c
Protein Family:Rab effector
UniProt Gene Name:MYRIP  
UniProt Entry Name:MYRIP_HUMAN
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