Cell Biology Antibodies 5

Anti-MYOZ1 Antibody (CAB14483)

(No reviews yet) Write a Review
SKU:
CAB14483
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-MYOZ1 Antibody
Antibody SKU:CAB14483
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 180-299 of human MYOZ1 (NP_067068.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:1000
Reactivity:Human, Mouse, Rat
Positive Samples:DU145, BxPC-3, A-549, Mouse liver, Mouse skeletal muscle, Mouse heart, Mouse thymus, Rat skeletal muscle
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 180-299 of human MYOZ1 (NP_067068.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:VFKT YISP WERA MGVD PQQK MELG IDLL AYGA KAEL PKYK SFNR TAMP YGGY EKAS KRMT FQMP KFDL GPLL SEPL VLYN QNLS NRPS FNRT PIPW LSSG EPVD YNVD IGIP LDGE TEEL
Gene ID:58529
Uniprot:Q9NP98
Cellular Location:Cell projection, Nucleus, pseudopodium
Calculated MW:31kDa
Observed MW:37kDa
Synonyms:MYOZ1, CS-2, FATZ, MYOZ
Background:The protein encoded by this gene is primarily expressed in the skeletal muscle, and belongs to the myozenin family. Members of this family function as calcineurin-interacting proteins that help tether calcineurin to the sarcomere of cardiac and skeletal muscle. They play an important role in modulation of calcineurin signaling.
UniProt Protein Function:MYOZ1: Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis. Belongs to the myozenin family.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 10q22.1

Cellular Component: pseudopodium; nucleus; actin cytoskeleton

Molecular Function:protein binding; FATZ binding

Biological Process: myofibril assembly

NCBI Summary:The protein encoded by this gene is primarily expressed in the skeletal muscle, and belongs to the myozenin family. Members of this family function as calcineurin-interacting proteins that help tether calcineurin to the sarcomere of cardiac and skeletal muscle. They play an important role in modulation of calcineurin signaling. [provided by RefSeq, Apr 2012]
UniProt Code:Q9NP98
NCBI GenInfo Identifier:74734300
NCBI Gene ID:58529
NCBI Accession:Q9NP98.1
UniProt Secondary Accession:Q9NP98,Q9H1I7,
UniProt Related Accession:Q9NP98
Molecular Weight:299
NCBI Full Name:Myozenin-1
NCBI Synonym Full Names:myozenin 1
NCBI Official Symbol:MYOZ1  
NCBI Official Synonym Symbols:CS-2; FATZ; MYOZ  
NCBI Protein Information:myozenin-1; MYOZ1; calsarcin-2; filamin-, actinin- and telethonin-binding protein
UniProt Protein Name:Myozenin-1
UniProt Synonym Protein Names:Calsarcin-2; Filamin-, actinin- and telethonin-binding protein; Protein FATZ
Protein Family:Myozenin
UniProt Gene Name:MYOZ1  
UniProt Entry Name:MYOZ1_HUMAN
Anti-MYOZ1 Antibody (CAB14483)Western blot analysis of extracts of various cell lines, using MYOZ1 antibody (CAB14483) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s.
View AllClose

0 Reviews

View AllClose

Related Products