Cell Biology Antibodies 5
Anti-MYOZ1 Antibody (CAB14482)
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- SKU:
- CAB14482
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-MYOZ1 Antibody |
| Antibody SKU: | CAB14482 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-299 of human MYOZ1 (NP_067068.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-299 of human MYOZ1 (NP_067068.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | VFKT YISP WERA MGVD PQQK MELG IDLL AYGA KAEL PKYK SFNR TAMP YGGY EKAS KRMT FQMP KFDL GPLL SEPL VLYN QNLS NRPS FNRT PIPW LSSG EPVD YNVD IGIP LDGE TEEL |
| Gene ID: | 58529 |
| Uniprot: | Q9NP98 |
| Cellular Location: | Cell projection, Nucleus, pseudopodium |
| Calculated MW: | 31kDa |
| Observed MW: | Refer to Figures |
| Synonyms: | MYOZ1, CS-2, FATZ, MYOZ |
| Background: | The protein encoded by this gene is primarily expressed in the skeletal muscle, and belongs to the myozenin family. Members of this family function as calcineurin-interacting proteins that help tether calcineurin to the sarcomere of cardiac and skeletal muscle. They play an important role in modulation of calcineurin signaling. |
| UniProt Protein Function: | MYOZ1: Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis. Belongs to the myozenin family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 10q22.1 Cellular Component: pseudopodium; nucleus; actin cytoskeleton Molecular Function:protein binding; FATZ binding Biological Process: myofibril assembly |
| NCBI Summary: | The protein encoded by this gene is primarily expressed in the skeletal muscle, and belongs to the myozenin family. Members of this family function as calcineurin-interacting proteins that help tether calcineurin to the sarcomere of cardiac and skeletal muscle. They play an important role in modulation of calcineurin signaling. [provided by RefSeq, Apr 2012] |
| UniProt Code: | Q9NP98 |
| NCBI GenInfo Identifier: | 74734300 |
| NCBI Gene ID: | 58529 |
| NCBI Accession: | Q9NP98.1 |
| UniProt Secondary Accession: | Q9NP98,Q9H1I7, |
| UniProt Related Accession: | Q9NP98 |
| Molecular Weight: | 299 |
| NCBI Full Name: | Myozenin-1 |
| NCBI Synonym Full Names: | myozenin 1 |
| NCBI Official Symbol: | MYOZ1 |
| NCBI Official Synonym Symbols: | CS-2; FATZ; MYOZ |
| NCBI Protein Information: | myozenin-1; MYOZ1; calsarcin-2; filamin-, actinin- and telethonin-binding protein |
| UniProt Protein Name: | Myozenin-1 |
| UniProt Synonym Protein Names: | Calsarcin-2; Filamin-, actinin- and telethonin-binding protein; Protein FATZ |
| Protein Family: | Myozenin |
| UniProt Gene Name: | MYOZ1 |
| UniProt Entry Name: | MYOZ1_HUMAN |
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